Solo ciò che funziona
Nessun ingrediente inutile, sottodosato o non supportato dagli studi. Se non è nell'elenco, è perché non serve davvero — o va preso separatamente.
PRE-ORDINE: Spedizioni dal 6 Novembre
Edoardo BaldiniFITNESS SCIENTIFICOProduzione limitata — 50 confezioni/giorno
Multivitaminico Scientifico 2.0Il Multivitaminico
Il Multivitaminico
Senza Stronz*te
Vitamine e minerali selezionati. Due capsule al giorno. Ogni scelta spiegata, fino all’ultimo ingrediente.
- Magnesio, zinco, vitamina D3 con K1 e K2, vitamine B ed E
- Forme attive e grado farmaceutico dove possibile
- Formula, analisi e studi scientifici da consultare prima di scegliere
Da 35 € per 30 giorni · 60 capsule per confezione
Spedizione gratuita in Italia · istruzioni e supporto inclusi
2Capsule al giorno
14+Micronutrienti attivi
100%Qualità dimostrabile
300+Studi scientifici
Ott '27Scadenza
Prima di scegliereLeggi la formula.
Leggi la formula.
Capisci la differenza.
Il valore di un multivitaminico si capisce da cosa contiene, in quali forme e in quali quantità.
Qui puoi controllare tutto: ingredienti e dosaggi per giornata, caratteristiche delle materie prime, analisi disponibili e motivi delle esclusioni. Le spiegazioni e gli studi sono raccolti nella stessa pagina, così puoi approfondire quanto vuoi.
Se assumi già magnesio, zinco, vitamine D e K o un complesso B separatamente, confronta le quantità prima di sommare i prodotti.
Solo 2 capsule al giorno — nessun ingrediente inutile, sottodosato o non supportato dagli studi. Forme attive e di grado farmaceutico dove possibile, dosaggi elevati, zero eccipienti superflui. Quello che il tuo corpo merita davvero.
✦ Forme Biodisponibili & Attive✦ Grado Farmaceutico dove possibile✦ Zero Eccipienti Superflui✦ Dosaggi Elevati✦ Senza Glutine & Lattosio✦ 14–80 anni · Uomo & Donna✦ Ok per mutazione MTHFR✦ Prodotto Manualmente
Forme attive dove possibile
Dove possibile, le forme attive delle vitamine e chelate dei minerali — fino a 10× più costose ma molto più assorbibili. La maggior parte dei brand non lo fa. Noi sì.
Grado farmaceutico dove possibile
Diversi ingredienti, dove disponibili in questa qualità, sono di grado farmaceutico — lo stesso usato nei farmaci. La maggior parte dei brand non lo fa nemmeno per un singolo ingrediente.
Zero eccipienti superflui
La capsula è riempita al massimo solo con vitamine e minerali. Nessun riempitivo e nessun eccipiente superfluo legato ai processi industriali. Produzione manuale: piena libertà formulativa.
Dosaggi elevati e mirati
Ogni ingrediente è nei dosaggi di mantenimento più studiati dalla letteratura scientifica, nel rispetto dei limiti di legge. Non il minimo indispensabile: il massimo utile in 2 capsule.
Per tutti. Davvero.
Uomini e donne, dai 14 agli 80 anni. Perfetto anche per chi ha la mutazione MTHFR (circa il 25% della popolazione). Senza glutine, senza lattosio, senza soia.
Scegli la tua quantità
SCEGLI L'OPZIONE GIUSTA PER TE
Ogni confezione contiene 60 capsule: 30 giorni alla dose di 2 capsule al giorno.
Preordine · spedizioni dal 6 novembreSCADENZA OTTOBRE 2027!Spedizione gratuita in Italia
12 confezioni
360 giorni totali · 2 capsule al giorno
356 €
Spedizione in Italia inclusa
Ordina 12 confezioniPer un uso condiviso o per un consumo entro ottobre 2027.
9 confezioni
270 giorni totali · 2 capsule al giorno
267 €
Spedizione in Italia inclusa
Ordina 9 confezioni
6 confezioni
180 giorni totali · 2 capsule al giorno
179 €
Spedizione in Italia inclusa
Ordina 6 confezioniTutte le altre quantità
5 confezioni
150 giorni totali · 2 capsule al giorno
149 €
Spedizione in Italia inclusa
Ordina 5 confezioni
3 confezioni
90 giorni totali · 2 capsule al giorno
90 €
Spedizione in Italia inclusa
Ordina 3 confezioni
2 confezioni
60 giorni totali · 2 capsule al giorno
60 €
Spedizione in Italia inclusa
Ordina 2 confezioni
1 confezione
30 giorni totali · 2 capsule al giorno
35 €
Spedizione in Italia inclusa
Ordina 1 confezione(Riceverai dentro il pacco tutte le istruzioni su come utilizzarlo)
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Per spedizioni estere o quantitativi particolari: scrivici su WhatsApp.
QUALI SONO GLI INGREDIENTI?
In sole 2 capsule è stato inserito il massimo quantitativo possibile di micronutrienti consentito dalla normativa, ed è il multivitaminico con il maggior numero di vitamine in forma attiva e, dove possibile, di grado farmaceutico.
✓
Non dovrai più comprare un integratore ZMA (o di Magnesio e Zinco separati).
✓
Non dovrai più comprare un integratore di mantenimento di Vitamina D e K.
✓
Non dovrai più comprare un complesso di Vitamine B: hai già i giusti ingredienti e le forme attive, incluse quelle che contribuiscono al normale metabolismo dell'omocisteina.
✓
Non manca niente. Quello che NON c'è è perché gli studi indicano che la maggior parte delle persone non ne è carente.
✕
Non contiene Soia, Glutine o Lattosio.
Informazioni nutrizionali
1 confezione: 60 capsule · dimensione 00, circa 23 mm
| Ingrediente, forma e caratteristiche | Per 2 capsule |
|---|---|
| Magnesio · citrato tribasico anidro | 200 mg |
| Zinco · picolinato | 15 mg |
| Vitamina D3 · colecalciferoloGrado farmaceutico · 100% BASF | 2.000 UI |
| Vitamina K1 + K2Titolazioni: 5% e 0,2% | 200 mcg |
| Vitamina B1Grado farmaceutico | 15 mg |
| Vitamina B2Grado farmaceutico | 2 mg |
| Vitamina B3 · nicotinamideForma attiva · Grado farmaceutico | 15 mg |
| Vitamina B5Grado farmaceutico | 10 mg |
| Vitamina B6 · piridossal-5-fosfatoForma attiva | 5 mg |
| BiotinaGrado farmaceutico · Titolazione 100% | 100 mcg |
| Folato · calcio L-metilfolatoForma attiva | 400 mcg |
| Vitamina B12 · metilcobalaminaForma attiva | 100 mcg |
| Vitamina E · EVNol™ MAX 20%Tocotrienoli e tocoferolo naturali | 6 mg |
Riepilogo di dosaggi, forme, grado farmaceutico e titolazioni riportati nella documentazione originale della pagina. 1 confezione: 60 capsule, dimensione 00 (circa 23 mm). Per i dettagli completi consulta anche l’etichetta e le istruzioni nel pacco.
INGREDIENTI: Idrossipropilmetilcellulosa (capsula di origine vegetale), Magnesio citrato tribasico anidro, Vitamina K2 naturale (Menachinone - Titolazione 0,2%), Zinco picolinato, Vitamina E EVNol™ 20% (miscela di α-tocoferolo e α-, β-, γ-, e δ- tocotrienoli naturali), Vitamina B1 (Tiamina cloridato - FU-Ph.Eur.), Vitamina B3 (Nicotinamide- FU-Ph.Eur.), Vitamina B5 (Calcio D-pantotenato - FU-Ph.Eur.), Vitamina D3 (Colecalciferolo), Vitamina B6 (Piridossal-5-fosfato), Vitamina B2 (Riboflavina - FU-Ph.Eur.), Vitamina K1 (Fillochinone - Titolazione 5%), Calcio L-metilfolato, Biotina (Titolazione 100% - FU-Ph.Eur.), Vitamina B12 (Metilcobalamina).
Vuoi le certificazioni e le analisi? Nessun problema. Scrivi a ufficio@baldiniedoardo.com
PERCHÉ È DIVERSO?
Il Magnesio è in forma biodisponibile e nel giusto dosaggio?
✓ Senza Stronz*te
Sì: Citrato tribasico anidro (forma chelata), in dosaggio in linea con la letteratura.
✕ Molti altri brand
Spesso ossido o solfato, forme meno assorbibili usate per raggiungere il dosaggio a basso costo.
Lo Zinco è in forma biodisponibile?
✓ Senza Stronz*te
Sì: Picolinato (forma chelata).
✕ Molti altri brand
Spesso ossido o solfato.
L'Acido Folico è in forma attiva?
✓ Senza Stronz*te
Sì: Calcio L-metilfolato (forma attiva), fino a 18× più costosa per i produttori.
✕ Molti altri brand
Spesso acido folico classico, meno assorbibile, per contenere i costi.
Il complesso di Vitamina B è in forma attiva?
✓ Senza Stronz*te
Sì, dove possibile: il maggior numero di vitamine B in forma attiva e in dosaggi corretti.
✕ Molti altri brand
Spesso nessuna vitamina B in forma attiva, o solo 1-2.
Quante forme di Vitamina K?
✓ Senza Stronz*te
Sia K2 naturale che K1.
✕ Molti altri brand
Quando presente, spesso una sola forma.
Contiene entrambe le famiglie di componenti della Vitamina E?
✓ Senza Stronz*te
Sì: 1 tocoferolo + 4 tocotrienoli, opzione fino a 12× più costosa per i produttori.
✕ Molti altri brand
Quando presente, di solito solo 1 tocoferolo.
La materia prima è di grado farmaceutico?
✓ Senza Stronz*te
Dove possibile sì. Anche dove non lo è, la titolazione (% di principio attivo) è sempre dichiarata.
✕ Molti altri brand
Spesso materia prima di grado alimentare, senza titolazione dichiarata.
Il prezzo riflette la qualità della formula?
✓ Senza Stronz*te
Con tutti gli ingredienti e i dosaggi corretti, il prezzo riflette la qualità reale delle forme usate.
✕ Molti altri brand
Prezzi molto bassi possibili solo con forme economiche e meno assorbibili.
2 SOLE CAPSULE AL GIORNO
✓ per coprire i fabbisogni quotidiani più comuni
✓ per tutte le età (20, 40, 60, 80 anni)
✓ sia per uomo che per donna
✓ adatto anche a chi ha la mutazione MTHFR (circa il 25% della popolazione)
*La maggior parte dei multivitaminici, per arrivare a dosaggi simili, richiede almeno 3 capsule al giorno.
Confronto basato sulle caratteristiche di formulazione. "Molti altri brand" si riferisce a prassi comuni di mercato, non a un produttore specifico.
TUTTO PRODOTTO A MANO
un vantaggio unico
Il fatto che il MULTIVITAMINICO SENZA STRONZ*TE sia prodotto manualmente ti permette di avere un vero e proprio gioiellino dell'integrazione.
✓
Mi garantisce piena libertà formulativa, che mi ha permesso di costruire una formulazione in linea con la letteratura scientifica (cosa che nei processi industriali dei grandi brand spesso non è possibile).
✓
Questo ti permette di sfruttare al meglio ciò che assumi, perché si rispettano forme e dosaggi studiati dalla letteratura.
✓
Non sei costretto ad assumere eccipienti superflui: non dobbiamo inserirli. Nei processi industriali di molti grossi brand, invece, servono a far funzionare i macchinari.
✓
Ogni capsula è riempita al massimo della sua capacità: hai il dosaggio pieno (nel rispetto dei limiti di legge) per capsula, senza assumere capsule in più né pagare il costo extra delle capsule.
È anche il motivo per cui produciamo solo 50 confezioni al giorno, invece delle centinaia fabbricate industrialmente dai grossi brand.
Questo ti garantisce una qualità reale e dimostrabile.
MATERIA PRIMA GARANTITA
Grado Farmaceutico dove possibile
Molti ingredienti, dove è stato possibile trovarli, sono di grado farmaceutico: una qualità così alta da poter essere usata anche nei farmaci. Dato che non è obbligatorio, la maggior parte dei brand non lo fa nemmeno su un singolo ingrediente.
Perché allora l'abbiamo usata?
GRADO FARMACEUTICO
Materia prima che ha obbligatoriamente i propri certificati di analisi con titolazione. Ti dà la tranquillità che la percentuale di principio attivo è verificata e dichiarata e che l'origine è conosciuta.
GRADO ALIMENTARE
Si chiama grado food: in assenza di titolazione non si conosce con certezza la quantità di principio attivo. Per prodotti non realizzati in Italia, in molti casi mancano anche garanzie sull'origine.
E dove non è stata trovata di grado farmaceutico, mi sono comunque assicurato che fosse nota la titolazione. Quindi, in un modo o nell'altro, hai sempre queste informazioni.
Vuoi scaricare il report? Clicca qui
MINERALI NELLE MIGLIORI FORME
Forme Chelate
Devi sapere che non tutte le forme dei minerali sono uguali. Esistono le cosiddette forme chelate e le forme non chelate (quelle classiche).
Le forme chelate sono l'equivalente delle forme attive, ma per i minerali: quando troviamo una forma chelata, significa che è più biodisponibile, ovvero maggiormente assorbita dal corpo.
In pratica si combina un minerale con un agente chelante (di solito un amminoacido o un acido organico), e questo ne aumenta l'assorbimento.
In uno studio, la forma chelata/citrato dello Zinco risultava assorbita meglio rispetto all'ossido.
Lo stesso vale per il Magnesio: il citrato mostra una biodisponibilità superiore rispetto all'ossido.
VITAMINE NELLE FORME ATTIVE
e più complete
Dove possibile sono state inserite le forme attive delle vitamine. Cosa che i brand di integrazione normalmente non fanno, perché a parità di dosaggio possono costare anche 10× più delle forme inattive.
Sono però molto migliori in termini di assorbimento, e la differenza è documentata.
In uno studio, la forma attiva della Vitamina B12 (metilcobalamina) risultava assorbita meglio rispetto alla forma non attiva, spesso più utilizzata.
Riferimenti (PubMed PMID): 28223907
Inoltre sono state inserite vitamine che spesso non si trovano, ma che hanno la loro importanza. Per esempio la Vitamina E (composta da 4 tocoferoli e 4 tocotrienoli): la maggior parte dei brand, quando la inserisce, mette solo 1 tocoferolo. Qui trovi 1 tocoferolo + 4 tocotrienoli.
La Vitamina D, poi, è bene accompagnarla sempre con la Vitamina K per un miglior equilibrio nel loro utilizzo. Per questo sono state inserite entrambe, ai giusti dosaggi.
E per di più non è stata inserita una sola forma di Vitamina K, come spesso accade: sono state inserite entrambe (K1 e K2). Il motivo è che i diversi tipi di Vitamina K hanno un metabolismo e una distribuzione differenti nel corpo.
Per questo prendere più forme ha senso, per un miglior assorbimento.
Chi c’è dietro la formula
Sono Edoardo Baldini.
Mi occupo di divulgazione sul fitness scientifico dal 2016. In oltre 10 anni sono stato una delle pochissime persone del settore a non accettare mai codici sconto o sponsorizzazioni dai brand.
Stanco della spazzatura che circola in rete, ho deciso di creare i miei composti scientifici: formule costruite partendo dagli studi, con ingredienti, forme e dosaggi spiegati apertamente.
È da qui che nasce il Multivitaminico Senza Stronz*te. In questa pagina ti spiego perché ho inserito ogni nutriente, in quale forma e con quale dosaggio. Anche quello che ho lasciato fuori ha una ragione: la trovi qui sotto.
Hai una domanda prima di ordinare? Scrivimi via email oppure contattaci su WhatsApp.
La formula spiegata
PERCHÈ CI SONO QUESTI INGREDIENTI?
01 / LA FORMULA, SPIEGATA
MAGNESIO
200 mgMagnesio citrato · per 2 capsule
Nel "Multivitaminico Senza Stronz*te" il Magnesio è nella forma Citrato tribasico anidro — una forma chelata, scelta per la sua qualità.
È un minerale che si perde facilmente, anche con la sudorazione, e una parte importante della popolazione non ne raggiunge il fabbisogno giornaliero con la sola alimentazione.
Perché ho scelto la forma Citrato
Stando alle informazioni scientifiche, la forma Citrato è tra le più facilmente assorbite e tollerate, con una biodisponibilità superiore rispetto alle forme più economiche come l'ossido. È il motivo per cui ho scelto questa forma invece di quelle che molti brand usano per contenere i costi.
Funzioni riconosciute del Magnesio
✓ Contribuisce alla riduzione di stanchezza e affaticamento
✓ Contribuisce al normale funzionamento del sistema nervoso e alla normale funzione psicologica
✓ Contribuisce alla normale funzione muscolare
✓ Contribuisce al mantenimento di ossa e denti normali
✓ Contribuisce al normale metabolismo energetico e all'equilibrio elettrolitico
Indicazioni sulla salute autorizzate ai sensi del Reg. (UE) 432/2012.
Ho inserito il quantitativo più alto possibile in 2 capsule, nel rispetto dei limiti di legge:
Magnesio Citrato 200mg
(citrato tribasico anidro)
Tutti gli studi consultati per la formulazione sono raccolti nella bibliografia in fondo alla pagina.
02 / LA FORMULA, SPIEGATA
ZINCO
15 mgZinco picolinato · per 2 capsule
Nel "Multivitaminico Senza Stronz*te" lo Zinco è nella forma Picolinato, una forma chelata.
Anche lo Zinco si perde facilmente con la sudorazione, quindi chi fa sport può doverci prestare ancora più attenzione attraverso l'alimentazione.
Funzioni riconosciute dello Zinco
✓ Contribuisce al mantenimento di normali livelli di testosterone nel sangue
✓ Contribuisce alla normale fertilità e riproduzione
✓ Contribuisce alla normale funzione del sistema immunitario
✓ Contribuisce alla protezione delle cellule dallo stress ossidativo
✓ Contribuisce al normale metabolismo dei macronutrienti e all'equilibrio acido-base
Indicazioni sulla salute autorizzate ai sensi del Reg. (UE) 432/2012.
Perché ho scelto la forma Picolinato
Tra le forme di zinco, stando alle informazioni scientifiche il Picolinato è una delle più studiate per l'assorbimento e potrebbe essere tra le migliori da questo punto di vista. È la forma che ho scelto per il multivitaminico.
Riferimenti (PubMed PMID): 3630857
Zinco e Vitamina D lavorano in sinergia: per questo nel multivitaminico sono presenti entrambi, così da supportarsi a vicenda nel loro utilizzo.
Riferimenti completi nella bibliografia in fondo alla pagina.
Ho inserito il quantitativo più alto possibile in 2 capsule, nel rispetto dei limiti di legge:
Zinco Picolinato 15mg
03 / LA FORMULA, SPIEGATA
VITAMINA D & VITAMINA K
2.000 UIVitamina D3 · con K1 e K2
La Vitamina D è uno dei micronutrienti più importanti per l'organismo. La produciamo soprattutto attraverso l'esposizione al sole e, secondo la letteratura, una parte importante della popolazione ha apporti inferiori ai livelli raccomandati — anche perché non passa abbastanza tempo all'aria aperta nel modo corretto.
Con l'avanzare dell'età, inoltre, il corpo tende a sintetizzarne di meno a parità di esposizione.
Funzioni riconosciute della Vitamina D
✓ Contribuisce alla normale funzione del sistema immunitario
✓ Contribuisce al mantenimento di ossa e denti normali
✓ Contribuisce alla normale funzione muscolare
✓ Contribuisce al normale assorbimento e utilizzo di calcio e fosforo
✓ Ha un ruolo nel processo di divisione cellulare
Indicazioni sulla salute autorizzate ai sensi del Reg. (UE) 432/2012.
In assenza di analisi del sangue, la letteratura indica un dosaggio di mantenimento tra 400 e 2000 UI. Ho scelto il valore più alto di questo intervallo, in forma di grado farmaceutico:
Vitamina D 2000 UI
(grado farmaceutico, 100% BASF)
È tra i dosaggi più alti che si trovino in un multivitaminico, pur restando entro i limiti di sicurezza e di legge: molti prodotti si fermano molto più in basso.
Riferimenti (PubMed PMID): 16825677
E la Vitamina K?
Alla Vitamina D ho abbinato la giusta dose di Vitamina K, in entrambe le forme (K1 + K2).
È una differenza concreta rispetto a molti altri prodotti sul mercato: la maggior parte dei brand, quando inserisce la Vitamina K, ne mette una sola forma — o non la inserisce affatto. Qui trovi sia la K1 che la K2.
Il motivo è che le due forme hanno un metabolismo e una distribuzione differenti nel corpo, e D e K lavorano bene insieme: per questo le ho pensate in abbinamento, ai giusti dosaggi.
Funzioni riconosciute della Vitamina K
✓ Contribuisce alla normale coagulazione del sangue
✓ Contribuisce al mantenimento di ossa normali
Indicazioni sulla salute autorizzate ai sensi del Reg. (UE) 432/2012.
Tutti gli studi consultati per la formulazione sono raccolti nella bibliografia in fondo alla pagina.
04 / LA FORMULA, SPIEGATA
COMPLESSO VITAMINE B
8 vitamineIl complesso B della formula
Non esiste una sola vitamina B: ne esistono diverse, ognuna con il suo ruolo. Nel "Multivitaminico Senza Stronz*te" sono state inserite le principali e più studiate, ai giusti dosaggi e, dove possibile, in forma attiva.
Sono micronutrienti che la sudorazione, un'alimentazione non equilibrata o problemi di assorbimento possono ridurre. Vediamole una per una.
Acido Folico (B9) — in forma attiva (L-metilfolato)
Inserito nella forma attiva (L-metilfolato), più rara da trovare nei multivitaminici e ben utilizzabile anche da chi ha la mutazione MTHFR, senza che ciò implichi che l’acido folico classico sia inefficace per tutte le comuni varianti MTHFR. Nella Formulazione 2.0 la dose è stata portata a 400mcg.
Contribuisce al normale metabolismo dell'omocisteina, alla normale funzione psicologica, alla riduzione di stanchezza e affaticamento e alla normale ematopoiesi.
Vitamina B12 — in forma attiva
Inserita nella forma attiva. Con l'avanzare dell'età il corpo tende ad assorbirne meno da ciò che si mangia, ed è una delle vitamine a cui prestare attenzione anche per chi è molto concentrato a lungo (es. studenti).
Contribuisce al normale metabolismo energetico, alla normale funzione del sistema nervoso, alla normale formazione dei globuli rossi, al normale metabolismo dell'omocisteina e alla riduzione di stanchezza e affaticamento.
Riferimenti (PubMed PMID): 19904199
Vitamina B6 — in forma attiva
Inserita nella forma attiva. Interviene nel metabolismo di proteine e carboidrati e nella normale formazione dei globuli rossi.
Contribuisce al normale metabolismo dell'omocisteina, alla regolazione dell'attività ormonale, al normale metabolismo energetico e alla riduzione di stanchezza e affaticamento.
Vitamina B3 — forma nicotinammide
Inserita nella forma nicotinammide, ben tollerata e facilmente utilizzabile.
Contribuisce al normale metabolismo energetico, alla normale funzione psicologica e alla riduzione di stanchezza e affaticamento.
Biotina — grado farmaceutico, forma attiva
Inserita alla titolazione massima possibile (100%), di grado farmaceutico e in forma attiva.
Contribuisce al mantenimento di pelle e capelli normali, al normale metabolismo energetico e alla normale funzione psicologica.
Perché le forme attive?
Vitamina B6, B9 e B12 sono state inserite, dove possibile, in forma attiva: una scelta più costosa che molti brand non fanno, ma che permette al corpo di utilizzarle senza doverle prima convertire — un vantaggio in particolare per chi ha la mutazione MTHFR.
Tutti gli studi consultati per la formulazione sono raccolti nella bibliografia in fondo alla pagina.
05 / LA FORMULA, SPIEGATA
VITAMINA E
1 + 4Tocoferolo + tocotrienoli
La Vitamina E non è una sola molecola: è composta da 4 tocoferoli e 4 tocotrienoli. La maggior parte dei brand, quando la inserisce, mette solo 1 tocoferolo.
Nel "Multivitaminico Senza Stronz*te" trovi invece 1 tocoferolo + 4 tocotrienoli: una forma più completa, un'opzione anche più costosa per chi produce, ma che ho scelto per offrire un profilo più ampio.
Funzione riconosciuta della Vitamina E
✓ Contribuisce alla protezione delle cellule dallo stress ossidativo
Indicazione sulla salute autorizzata ai sensi del Reg. (UE) 432/2012.
Inserire entrambe le famiglie di componenti, anziché il solo tocoferolo, è una scelta che pochi brand fanno: è uno dei dettagli che distinguono questa formula, nel rispetto dei limiti di legge.
06 / LA FORMULA, SPIEGATA
PERCHÉ ALCUNI NON CI SONO?
Le esclusioniOgni scelta ha una spiegazione
Te lo spiego apertamente, perché fa parte del "senza stronz*te": alcuni nutrienti non sono stati inseriti di proposito. Ecco il perché, uno per uno.
La Vitamina C
È importante — contribuisce alla protezione delle cellule dallo stress ossidativo, alla normale funzione del sistema immunitario e alla normale formazione del collagene per pelle, ossa e cartilagine. Per offrire dosaggi nell’ordine di 1–2 grammi ho preferito un prodotto separato: inserirli in 2 capsule significherebbe sacrificare lo spazio per gli altri ingredienti. Queste quantità sono una scelta di formulazione e non il fabbisogno quotidiano di tutti.
Per questo ho creato un prodotto dedicato: l'Antiossidante Senza Stronz*te, che fornisce la Vitamina C in forma liposomiale, a un dosaggio adeguato.
Il Rame
Statisticamente la maggior parte delle persone raggiunge il proprio fabbisogno con la sola alimentazione, quindi il rischio di carenza è basso. Qualora servisse, è meglio integrarlo con un prodotto specifico, non con un multivitaminico.
Va inoltre considerato che un’assunzione elevata e protratta di zinco può ridurre l’assorbimento del rame. La formula contiene 15 mg di zinco: considera anche gli altri integratori che eventualmente assumi.
Il Ferro
Il Ferro non andrebbe integrato "a caso": se non necessario, non è privo di controindicazioni. Per questo si assume solo quando serve davvero, e meglio da solo o al massimo insieme alla Vitamina C.
Inoltre Zinco e Ferro assunti insieme possono entrare in contrasto di assorbimento: un altro motivo per tenerlo fuori da un multivitaminico.
Il Calcio
Situazione simile: la maggior parte delle persone non risulta avere apporti carenti, e se assunto insieme al Magnesio può entrare in contrasto, riducendo l'assorbimento totale.
Riferimenti (PubMed PMID): 10930201
Il Selenio
Il Selenio si trova in diversi alimenti. Le noci del Brasile ne sono particolarmente ricche: una noce può contenerne circa 70–90 mcg, con ampia variabilità. Il fabbisogno non è universalmente di 200–300 mcg: le quantità raccomandate dipendono dall’età e dalla condizione individuale. Per questo ho scelto di non inserirlo automaticamente nella formula; un’eventuale integrazione va valutata in base all’alimentazione e alle esigenze individuali.
La logica è sempre la stessa: dentro solo ciò che ha senso averci, ai dosaggi che contano. Ciò che si ottiene facilmente con la dieta, o che merita un dosaggio dedicato, sta meglio fuori.
Approfondimenti sulle precisazioni di zinco e selenio: NIH ODS · Zinco · NIH ODS · Selenio.
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Prima e dopo l’acquisto
DOMANDE FREQUENTI
È adatto ai Vegani? È senza Lattosio? È senza glutine?
Purtroppo la vitamina k2 non rende possibile l'utilizzo per vegani.
Il Multivitaminico però è senza glutine e senza lattosio.
Dopo quanto riceverò l'integratore? La spedizione è tracciata?
Sì, la spedizione è tracciata. Questo è un preordine: le spedizioni iniziano dal 6 novembre. La consegna è prevista in 2 giorni lavorativi dall’affidamento al corriere.
Posso pagare con bonifico? Posso pagare in contrassegno?
Contrassegno: non è possibile pagare con il contrassegno.
Bonifico: È possibile. I dati sono i seguenti.
Farmacia degli Ulivi s.r.l.
BANCO INTESA SANPAOLO
IBAN: IT93 T03069 64716 1000 0000 4961
Appena fatto invia la contabile a questa email: ufficio@baldiniedoardo.com
Qual è la data di scadenza?
La scadenza del lotto indicato in questa pagina è ottobre 2027. Scegli una quantità consumabile entro la scadenza, considerando anche il numero di utilizzatori.
Qual è la dimensione della capsula?
Va bene sia per Uomo, che per Donna?
Sì, va bene sia per uomo, che per donna.
Le donne, se in pre-menopausa, potrebbero aver la necessità di aggiungere un integratore di ferro qualora la propria alimentazione ne fosse deficitaria.
Ho domande sullo stato del mio ordine
Puoi scrivere al +39 333 9118811 su WhatsApp oppure a ufficio@baldiniedoardo.com.
Ho domande prima di acquistare l'integratore
Puoi scrivere una email a ebassistance@gmail.com o un messaggio whatsapp al +393339118811.
Qual è il momento giusto per prendere il Multivitaminico?
Idealmente con un pasto non contenente tanti fitati (si trovano soprattutto nei cerali e nei legumi).
Idealmente con un pasto contenente dei grassi (in modo da assorbire al massimo la Vitamina D).
Se avrò domande sull'utilizzo dell'integratore?
Avrai accesso ad un'email riservata per il supporto specifico a questo integratore.
Va bene se ho 20, 40, 60, 90 anni?
Sì, l'integratore è stato creato con l'obiettivo di prevenire qualsiasi carenza che la maggior parte delle persone può ritrovarsi ad avere
Fonti e approfondimenti
QUALI STUDI SCIENTIFICI SONO STATI USATI?
Il quantitativo di studi utilizzati per la creazione del
"Multivitaminico senza Stronz*te"
richiederebbe un sito apposito.
Qui di seguito però ti lascio i principali,
oltre a quelli già mostrati in questa pagina:
La bibliografia riguarda i nutrienti, le forme e gli argomenti discussi. Forma, dosaggio e popolazione studiata vanno considerati quando si interpreta ciascun risultato.
MAGNESIO97 riferimenti
- Triglycerides - Kishimoto Y, Tani M, Uto-Kondo H, Saita E, Iizuka M, Sone H, Yokota K, Kondo KEffects of magnesium on postprandial serum lipid responses in healthy human subjectsBr J Nutr.(2010 Feb)
- Osteocalcin - Doyle L, Flynn A, Cashman KThe effect of magnesium supplementation on biochemical markers of bone metabolism or blood pressure in healthy young adult femalesEur J Clin Nutr.(1999 Apr)
- Blood Pressure - Sacks FM, Willett WC, Smith A, Brown LE, Rosner B, Moore TJEffect on blood pressure of potassium, calcium, and magnesium in women with low habitual intakeHypertension.(1998 Jan)
- Blood Pressure - Joëlle C Schutten, Peter J Joris, Iris Groendijk, Coby Eelderink, Dion Groothof, Yvonne van der Veen, Ralf Westerhuis, Frans Goorman, Richard M Danel, Martin H de Borst, Stephan J L BakkerEffects of Magnesium Citrate, Magnesium Oxide, and Magnesium Sulfate Supplementation on Arterial Stiffness: A Randomized, Double-Blind, Placebo-Controlled Intervention TrialJ Am Heart Assoc.(2022 Mar 15)
- Blood Pressure - Byrne J, Murphy C, Keogh JB, Clifton PMThe Effect of Magnesium Supplementation on Endothelial Function: A Randomised Cross-Over Pilot Study.Int J Environ Res Public Health.(2021-Aug-02)
- Blood Pressure - Murphy C, Byrne J, Keogh JB, Headland ML, Clifton PMThe Acute Effect of Magnesium Supplementation on Endothelial Function: A Randomized Cross-Over Pilot Study.Int J Environ Res Public Health.(2021-May-17)
- Blood glucose - de Valk HW, Verkaaik R, van Rijn HJ, Geerdink RA, Struyvenberg AOral magnesium supplementation in insulin-requiring Type 2 diabetic patientsDiabet Med.(1998 Jun)
- Blood glucose - Guerrero-Romero F, Rodríguez-Morán MThe effect of lowering blood pressure by magnesium supplementation in diabetic hypertensive adults with low serum magnesium levels: a randomized, double-blind, placebo-controlled clinical trialJ Hum Hypertens.(2009 Apr)
- Blood glucose - Rodríguez-Morán M, Guerrero-Romero FOral magnesium supplementation improves insulin sensitivity and metabolic control in type 2 diabetic subjects: a randomized double-blind controlled trialDiabetes Care.(2003 Apr)
- Blood Pressure - Verma H, Garg REffect of magnesium supplementation on type 2 diabetes associated cardiovascular risk factors: a systematic review and meta-analysisJ Hum Nutr Diet.(2017 Oct)
- Blood Pressure - Asbaghi O, Hosseini R, Boozari B, Ghaedi E, Kashkooli S, Moradi SThe Effects of Magnesium Supplementation on Blood Pressure and Obesity Measure Among Type 2 Diabetes Patient: a Systematic Review and Meta-analysis of Randomized Controlled Trials.Biol Trace Elem Res.(2021-Feb)
- Serum Magnesium - de Lordes Lima M, Cruz T, Pousada JC, Rodrigues LE, Barbosa K, Canguçu VThe effect of magnesium supplementation in increasing doses on the control of type 2 diabetesDiabetes Care.(1998 May)
- Serum Magnesium - Zamani M, Haghighat NThe Effects of Magnesium Supplementation on Serum Magnesium and Calcium Concentration in Patients With Type 2 Diabetes: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.Clin Nutr Res.(2022-Apr)
- HbA1c - Nicola Veronese, Ligia J Dominguez, Damiano Pizzol, Jacopo Demurtas, Lee Smith, Mario BarbagalloOral Magnesium Supplementation for Treating Glucose Metabolism Parameters in People with or at Risk of Diabetes: A Systematic Review and Meta-Analysis of Double-Blind Randomized Controlled TrialsNutrients.(2021 Nov 15)
- HbA1c - Chua FB, Cinco JE, Paz-Pacheco EEfficacy of Magnesium Supplementation on Glycemic Control in Type 2 Diabetes Patients: A Meta-analysis.J ASEAN Fed Endocr Soc.(2017)
- HbA1c - Asbaghi O, Moradi S, Kashkooli S, Zobeiri M, Nezamoleslami S, Hojjati Kermani MA, Lazaridi AV, Miraghajani MThe effects of oral magnesium supplementation on glycaemic control in patients with type 2 diabetes: a systematic review and dose-response meta-analysis of controlled clinical trials.Br J Nutr.(2022-Dec-28)
- Triglycerides - Asbaghi O, Moradi S, Nezamoleslami S, Moosavian SP, Hojjati Kermani MA, Lazaridi AV, Miraghajani MThe Effects of Magnesium Supplementation on Lipid Profile Among Type 2 Diabetes Patients: a Systematic Review and Meta-analysis of Randomized Controlled Trials.Biol Trace Elem Res.(2021-Mar)
- Osteocalcin - Aydin H, Deyneli O, Yavuz D, Gözü H, Mutlu N, Kaygusuz I, Akalin SShort-term oral magnesium supplementation suppresses bone turnover in postmenopausal osteoporotic womenBiol Trace Elem Res.(2010 Feb)
- Bone Mineral Density - Carpenter TO, DeLucia MC, Zhang JH, Bejnerowicz G, Tartamella L, Dziura J, Petersen KF, Befroy D, Cohen DA randomized controlled study of effects of dietary magnesium oxide supplementation on bone mineral content in healthy girlsJ Clin Endocrinol Metab.(2006 Dec)
- PMS Symptoms - De Souza MC, Walker AF, Robinson PA, Bolland KA synergistic effect of a daily supplement for 1 month of 200 mg magnesium plus 50 mg vitamin B6 for the relief of anxiety-related premenstrual symptoms: a randomized, double-blind, crossover studyJ Womens Health Gend Based Med.(2000 Mar)
- PMS Symptoms - Walker AF, De Souza MC, Vickers MF, Abeyasekera S, Collins ML, Trinca LAMagnesium supplementation alleviates premenstrual symptoms of fluid retentionJ Womens Health.(1998 Nov)
- PMS Symptoms - Quaranta S, Buscaglia MA, Meroni MG, Colombo E, Cella SPilot study of the efficacy and safety of a modified-release magnesium 250 mg tablet (Sincromag) for the treatment of premenstrual syndromeClin Drug Investig.(2007)
- PMS Symptoms - Ebrahimi E, Khayati Motlagh S, Nemati S, Tavakoli ZEffects of magnesium and vitamin b6 on the severity of premenstrual syndrome symptomsJ Caring Sci.(2012 Nov 22)
- PMS Symptoms - Facchinetti F, Borella P, Sances G, Fioroni L, Nappi RE, Genazzani AROral magnesium successfully relieves premenstrual mood changesObstet Gynecol.(1991 Aug)
- Blood glucose - Guerrero-Romero F, Rodríguez-Morán MMagnesium improves the beta-cell function to compensate variation of insulin sensitivity: double-blind, randomized clinical trialEur J Clin Invest.(2011 Apr)
- Blood glucose - Mooren FC, Krüger K, Völker K, Golf SW, Wadepuhl M, Kraus AOral magnesium supplementation reduces insulin resistance in non-diabetic subjects - a double-blind, placebo-controlled, randomized trialDiabetes Obes Metab.(2011 Mar)
- Blood glucose - Lee S, Park HK, Son SP, Lee CW, Kim IJ, Kim HJEffects of oral magnesium supplementation on insulin sensitivity and blood pressure in normo-magnesemic nondiabetic overweight Korean adultsNutr Metab Cardiovasc Dis.(2009 Dec)
- Blood glucose - Vedat Cinar, Yahya Polat, Rasim Mogulkoc, Mustafa Nizamlioglu, Abdulkerim Kasim BaltaciThe effect of magnesium supplementation on glucose and insulin levels of tae-kwan-do sportsmen and sedentary subjectsPak J Pharm Sci.(2008 Jul)
- Serum Magnesium - Guerrero-Romero F, Tamez-Perez HE, González-González G, Salinas-Martínez AM, Montes-Villarreal J, Treviño-Ortiz JH, Rodríguez-Morán MOral magnesium supplementation improves insulin sensitivity in non-diabetic subjects with insulin resistance. A double-blind placebo-controlled randomized trial.Diabetes Metab.(2004-Jun)
- Cortisol - Cinar V, Mogulkoc R, Baltaci AK, Polat YAdrenocorticotropic hormone and cortisol levels in athletes and sedentary subjects at rest and exhaustion: effects of magnesium supplementationBiol Trace Elem Res.(2008 Mar)
- C-Reactive Protein (CRP) - Nicola Veronese, Damiano Pizzol, Lee Smith, Ligia J Dominguez, Mario BarbagalloEffect of Magnesium Supplementation on Inflammatory Parameters: A Meta-Analysis of Randomized Controlled TrialsNutrients.(2022 Feb 5)
- C-Reactive Protein (CRP) - Talebi S, Miraghajani M, Hosseini R, Mohammadi HThe Effect of Oral Magnesium Supplementation on Inflammatory Biomarkers in Adults: A Comprehensive Systematic Review and Dose-response Meta-analysis of Randomized Clinical Trials.Biol Trace Elem Res.(2022-Apr)
- Testosterone - Cinar V, Polat Y, Baltaci AK, Mogulkoc REffects of magnesium supplementation on testosterone levels of athletes and sedentary subjects at rest and after exhaustionBiol Trace Elem Res.(2011 Apr)
- Muscle Soreness - Reno AM, Green M, Killen LG, O'Neal EK, Pritchett K, Hanson ZEffects of Magnesium Supplementation on Muscle Soreness and Performance.J Strength Cond Res.(2022-Aug-01)
- Muscle Soreness - Steward CJ, Zhou Y, Keane G, Cook MD, Liu Y, Cullen TOne week of magnesium supplementation lowers IL-6, muscle soreness and increases post-exercise blood glucose in response to downhill running.Eur J Appl Physiol.(2019-Dec)
- Creatine Kinase - Córdova A, Mielgo-Ayuso J, Roche E, Caballero-García A, Fernandez-Lázaro DImpact of Magnesium Supplementation in Muscle Damage of Professional Cyclists Competing in a Stage Race.Nutrients.(2019-Aug-16)
- LDL Oxidation - I De Leeuw, W Engelen, P Aerts, S SchransEffect of intensive magnesium supplementation on the in vitro oxidizability of LDL and VLDL in Mg-depleted type 1 diabetic patientsMagnes Res.(1998 Sep)
- Diabetic Neuropathy Symptoms - De Leeuw I, Engelen W, De Block C, Van Gaal LLong term magnesium supplementation influences favourably the natural evolution of neuropathy in Mg-depleted type 1 diabetic patients (T1dm)Magnes Res.(2004 Jun)
- Asthma Symptoms - Gontijo-Amaral C, Ribeiro MA, Gontijo LS, Condino-Neto A, Ribeiro JDOral magnesium supplementation in asthmatic children: a double-blind randomized placebo-controlled trialEur J Clin Nutr.(2007 Jan)
- Asthma Symptoms - Bede O, Surányi A, Pintér K, Szlávik M, Gyurkovits KUrinary magnesium excretion in asthmatic children receiving magnesium supplementation: a randomized, placebo-controlled, double-blind studyMagnes Res.(2003 Dec)
- Asthma Symptoms - Kazaks AG, Uriu-Adams JY, Albertson TE, Shenoy SF, Stern JSEffect of oral magnesium supplementation on measures of airway resistance and subjective assessment of asthma control and quality of life in men and women with mild to moderate asthma: a randomized placebo controlled trialJ Asthma.(2010 Feb)
- Asthma Symptoms - Fogarty A, Lewis SA, Scrivener SL, Antoniak M, Pacey S, Pringle M, Britton JOral magnesium and vitamin C supplements in asthma: a parallel group randomized placebo-controlled trialClin Exp Allergy.(2003 Oct)
- Blood Pressure - Hatzistavri LS, Sarafidis PA, Georgianos PI, Tziolas IM, Aroditis CP, Zebekakis PE, Pikilidou MI, Lasaridis ANOral magnesium supplementation reduces ambulatory blood pressure in patients with mild hypertensionAm J Hypertens.(2009 Oct)
- Blood Pressure - Kawano Y, Matsuoka H, Takishita S, Omae TEffects of magnesium supplementation in hypertensive patients: assessment by office, home, and ambulatory blood pressuresHypertension.(1998 Aug)
- Blood Pressure - Xi Zhang, Yufeng Li, Liana C Del Gobbo, Andrea Rosanoff, Jiawei Wang, Wen Zhang, Yiqing SongEffects of Magnesium Supplementation on Blood Pressure: A Meta-Analysis of Randomized Double-Blind Placebo-Controlled TrialsHypertension.(2016 Aug)
- Blood Pressure - Daniel T Dibaba, Pengcheng Xun, Yiqing Song, Andrea Rosanoff, Michael Shechter, Ka HeThe effect of magnesium supplementation on blood pressure in individuals with insulin resistance, prediabetes, or noncommunicable chronic diseases: a meta-analysis of randomized controlled trialsAm J Clin Nutr.(2017 Sep)
- Muscle Oxygenation - Golf SW, Bender S, Grüttner JOn the significance of magnesium in extreme physical stressCardiovasc Drugs Ther.(1998 Sep)
- Strength - L R Brilla, T F HaleyEffect of magnesium supplementation on strength training in humansJ Am Coll Nutr.(1992 Jun)
- Cramps - Nygaard IH, Valbø A, Pethick SV, Bøhmer TDoes oral magnesium substitution relieve pregnancy-induced leg crampsEur J Obstet Gynecol Reprod Biol.(2008 Nov)
- Cramps - Garrison SR, Birmingham CL, Koehler BE, McCollom RA, Khan KMThe effect of magnesium infusion on rest cramps: randomized controlled trial.J Gerontol A Biol Sci Med Sci.(2011-Jun)
- Cramps - Roffe C, Sills S, Crome P, Jones PRandomised, cross-over, placebo controlled trial of magnesium citrate in the treatment of chronic persistent leg cramps.Med Sci Monit.(2002-May)
- Cramps - Frusso R, Zárate M, Augustovski F, Rubinstein AMagnesium for the treatment of nocturnal leg cramps: a crossover randomized trial.J Fam Pract.(1999-Nov)
- Cramps - Olha Barna, Pavlo Lohoida, Yurii Holovchenko, Andrii Bazylevych, Valentyna Velychko, Iryna Hovbakh, Larysa Bula, Michael ShechterA randomized, double-blind, placebo-controlled, multicenter study assessing the efficacy of magnesium oxide monohydrate in the treatment of nocturnal leg crampsNutr J.(2021 Oct 31)
- Cramps - Liu J, Song G, Zhao G, Meng TEffect of oral magnesium supplementation for relieving leg cramps during pregnancy: A meta-analysis of randomized controlled trials.Taiwan J Obstet Gynecol.(2021-Jul)
- Cramps - Scott R Garrison, Christina S Korownyk, Michael R Kolber, G Michael Allan, Vijaya M Musini, Ravneet K Sekhon, Nicolas DugréMagnesium for skeletal muscle crampsCochrane Database Syst Rev.(2020 Sep 21)
- Pregnancy Complications - Kovács L, Molnár BG, Huhn E, Bódis L[Magnesium substitution in pregnancy. A prospective, randomized double-blind study].Geburtshilfe Frauenheilkd.(1988-Aug)
- Pregnancy Complications - Carla Adriane Leal de Araújo, Joel Geoffrey Ray, José Natal Figueiroa, João Guilherme AlvesBRAzil magnesium (BRAMAG) trial: a double-masked randomized clinical trial of oral magnesium supplementation in pregnancyBMC Pregnancy Childbirth.(2020 Apr 21)
- C-Reactive Protein (CRP) - Nielsen FH, Johnson LK, Zeng HMagnesium supplementation improves indicators of low magnesium status and inflammatory stress in adults older than 51 years with poor quality sleepMagnes Res.(2010 Dec)
- Sleep Quality - Held K, Antonijevic IA, Künzel H, Uhr M, Wetter TC, Golly IC, Steiger A, Murck HOral Mg(2+) supplementation reverses age-related neuroendocrine and sleep EEG changes in humansPharmacopsychiatry.(2002 Jul)
- Tinnitus Symptoms - Cevette MJ, Barrs DM, Patel A, Conroy KP, Sydlowski S, Noble BN, Nelson GA, Stepanek JPhase 2 study examining magnesium-dependent tinnitusInt Tinnitus J.(2011)
- Fibromyalgia Symptoms - Selda Bagis, Mehmet Karabiber, Ismet As, Lülüfer Tamer, Canan Erdogan, Ayçe AtalayIs magnesium citrate treatment effective on pain, clinical parameters and functional status in patients with fibromyalgia?Rheumatol Int.(2013 Jan)
- Serum Magnesium - Macian N, Dualé C, Voute M, Leray V, Courrent M, Bodé P, Giron F, Sonneville S, Bernard L, Joanny F, Menard K, Ducheix G, Pereira B, Pickering GShort-Term Magnesium Therapy Alleviates Moderate Stress in Patients with Fibromyalgia: A Randomized Double-Blind Clinical Trial.Nutrients.(2022-May-17)
- Fasting Glucose - Vázquez-Lorente H, Herrera-Quintana L, Molina-López J, Gamarra-Morales Y, López-González B, Miralles-Adell C, Planells EResponse of Vitamin D after Magnesium Intervention in a Postmenopausal Population from the Province of Granada, Spain.Nutrients.(2020-Jul-30)
- Body Mass Index (BMI) - Masoumeh Rafiee, Abed Ghavami, Ali Rashidian, Amir Hadi, Gholamreza AskariThe effect of magnesium supplementation on anthropometric indices: a systematic review and dose-response meta-analysis of clinical trialsBr J Nutr.(2020 Jul 28)
- Depression Symptoms - Barragán-Rodríguez L, Rodríguez-Morán M, Guerrero-Romero FEfficacy and safety of oral magnesium supplementation in the treatment of depression in the elderly with type 2 diabetes: a randomized, equivalent trialMagnes Res.(2008 Dec)
- Depression Symptoms - Afsharfar M, Shahraki M, Shakiba M, Asbaghi O, Dashipour AThe effects of magnesium supplementation on serum level of brain derived neurotrophic factor (BDNF) and depression status in patients with depression.Clin Nutr ESPEN.(2021-Apr)
- Depression Symptoms - Behnaz Abiri, Parvin Sarbakhsh, Mohammadreza VafaRandomized study of the effects of vitamin D and/or magnesium supplementation on mood, serum levels of BDNF, inflammation, and SIRT1 in obese women with mild to moderate depressive symptomsNutr Neurosci.(2021 Jul 2)
- Migraine Symptoms - Köseoglu E, Talaslioglu A, Gönül AS, Kula MThe effects of magnesium prophylaxis in migraine without auraMagnes Res.(2008 Jun)
- Migraine Symptoms - Hsiao-Yean Chiu, Tu-Hsueh Yeh, Yin-Cheng Huang, Pin-Yuan ChenEffects of Intravenous and Oral Magnesium on Reducing Migraine: A Meta-analysis of Randomized Controlled TrialsPain Physician.(2016 Jan)
- Migraine Severity - Kandil M, Jaber S, Desai D, Nuñez Cruz S, Lomotan N, Ahmad U, Cirone M, Burkins J, McDowell MMAGraine: Magnesium compared to conventional therapy for treatment of migraines.Am J Emerg Med.(2021-Jan)
- Headaches - Khani S, Hejazi SA, Yaghoubi M, Sharifipour EComparative study of magnesium, sodium valproate, and concurrent magnesium-sodium valproate therapy in the prevention of migraine headaches: a randomized controlled double-blind trial.J Headache Pain.(2021-Apr-07)
- Serum Magnesium - Behnood Abbasi, Masud Kimiagar, Khosro Sadeghniiat, Minoo M Shirazi, Mehdi Hedayati, Bahram RashidkhaniThe effect of magnesium supplementation on primary insomnia in elderly: A double-blind placebo-controlled clinical trialJ Res Med Sci.(2012 Dec)
- Serum Magnesium - Hornyak M, Voderholzer U, Hohagen F, Berger M, Riemann DMagnesium therapy for periodic leg movements-related insomnia and restless legs syndrome: an open pilot study.Sleep.(1998-Aug-01)
- Sleep Duration - Jasmine Mah, Tyler PitreOral magnesium supplementation for insomnia in older adults: a Systematic Review & Meta-AnalysisBMC Complement Med Ther.(2021 Apr 17)
- Stress Signs and Symptoms - Noah L, Dye L, Bois De Fer B, Mazur A, Pickering G, Pouteau EEffect of magnesium and vitamin B6 supplementation on mental health and quality of life in stressed healthy adults: Post-hoc analysis of a randomised controlled trial.Stress Health.(2021-Dec)
- Constipation Signs and Symptoms - Morishita D, Tomita T, Mori S, Kimura T, Oshima T, Fukui H, Miwa HSenna Versus Magnesium Oxide for the Treatment of Chronic Constipation: A Randomized, Placebo-Controlled Trial.Am J Gastroenterol.(2021-Jan-01)
- Constipation Signs and Symptoms - Kubota M, Ito K, Tomimoto K, Kanazaki M, Tsukiyama K, Kubota A, Kuroki H, Fujita M, Vandenplas YLactobacillus reuteri DSM 17938 and Magnesium Oxide in Children with Functional Chronic Constipation: A Double-Blind and Randomized Clinical Trial.Nutrients.(2020-Jan-15)
- Constipation Signs and Symptoms - Mori S, Tomita T, Fujimura K, Asano H, Ogawa T, Yamasaki T, Kondo T, Kono T, Tozawa K, Oshima T, Fukui H, Kimura T, Watari J, Miwa HA Randomized Double-blind Placebo-controlled Trial on the Effect of Magnesium Oxide in Patients With Chronic Constipation.J Neurogastroenterol Motil.(2019-Oct-30)
- Pre-Eclampsia Risk - de Araújo CAL, de Sousa Oliveira L, de Gusmão IMB, Guimarães A, Ribeiro M, Alves JGBMagnesium supplementation and preeclampsia in low-income pregnant women - a randomized double-blind clinical trial.BMC Pregnancy Childbirth.(2020-Apr-09)
- Fasting Glucose - Farsinejad-Marj M, Azadbakht L, Mardanian F, Saneei P, Esmaillzadeh AClinical and Metabolic Responses to Magnesium Supplementation in Women with Polycystic Ovary Syndrome.Biol Trace Elem Res.(2020-Aug)
- Insulin Resistance - Mohammad Alizadeh, Majid Karandish, Mohammad Asghari Jafarabadi, Lida Heidari, Roshan Nikbakht, Hossein Babaahmadi Rezaei, Reihaneh MousaviMetabolic and hormonal effects of melatonin and/or magnesium supplementation in women with polycystic ovary syndrome: a randomized, double-blind, placebo-controlled trialNutr Metab (Lond).(2021 Jun 6)
- Serum Magnesium - Reihaneh Mousavi, Mohammad Alizadeh, Mohammad Asghari Jafarabadi, Lida Heidari, Roshan Nikbakht, Hossein Babaahmadi Rezaei, Majid KarandishEffects of Melatonin and/or Magnesium Supplementation on Biomarkers of Inflammation and Oxidative Stress in Women with Polycystic Ovary Syndrome: a Randomized, Double-Blind, Placebo-Controlled TrialBiol Trace Elem Res.(2021 May 19)
- Quality of Life - Jaripur M, Ghasemi-Tehrani H, Askari G, Gholizadeh-Moghaddam M, Clark CCT, Rouhani MHThe effects of magnesium supplementation on abnormal uterine bleeding, alopecia, quality of life, and acne in women with polycystic ovary syndrome: a randomized clinical trial.Reprod Biol Endocrinol.(2022-Aug-02)
- ADHD Symptoms - Surman C, Vaudreuil C, Boland H, Rhodewalt L, DiSalvo M, Biederman JL-Threonic Acid Magnesium Salt Supplementation in ADHD: An Open-Label Pilot Study.J Diet Suppl.(2021)
- Fasting Glucose - Afitska K, Clavel J, Kisters K, Vormann J, Werner TMagnesium citrate supplementation decreased blood pressure and HbA1c in normomagnesemic subjects with metabolic syndrome: a 12-week, placebo-controlled, double-blinded pilot trial.Magnes Res.(2021-Aug-01)
- Cortisol - Schutten JC, Joris PJ, Minović I, Post A, van Beek AP, de Borst MH, Mensink RP, Bakker SJLLong-term magnesium supplementation improves glucocorticoid metabolism: A post-hoc analysis of an intervention trial.Clin Endocrinol (Oxf).(2021-Feb)
- Transferrin - Milinković N, Zeković M, Dodevska M, Đorđević B, Radosavljević B, Ignjatović S, Ivanović NMagnesium supplementation and iron status among female students: The intervention study.J Med Biochem.(2022-Jul-29)
- Serum Magnesium - Ali Reza Sobhani, Hossein Farshidi, Fariba Azarkish, Mahdiya Eslami, Ebrahim Eftekhar, Mansoor Keshavarz, Nepton SoltaniMagnesium Sulfate Improves Some Risk Factors for Atherosclerosis in Patients Suffering from One or Two Coronary Artery Diseases: A Double-blind Clinical Trial StudyClin Pharmacol.(2020 Sep 25)
- Fasting Glucose - Salehidoost R, Taghipour Boroujeni G, Feizi A, Aminorroaya A, Amini MEffect of oral magnesium supplement on cardiometabolic markers in people with prediabetes: a double blind randomized controlled clinical trial.Sci Rep.(2022-Oct-28)
- Fasting Glucose - Norouzi M, Rezvankhah B, Haeri MR, Heydari H, Tafaroji J, Shafigh N, Avval JO, Dahmardeh AR, Masoumzadeh N, Gharehbeglou MMagnesium supplementation and insulin resistance in patients with rheumatoid arthritis.Eur J Transl Myol.(2022-Jul-05)
- Pain - Hashemian M, Mirkheshti A, Mirafzal A, Ahmadipour H, Nasehabad MAThe effect of preoperative oral magnesium oxide on the severity of postoperative pain among women undergoing hysterectomy.Ir J Med Sci.(2022-Dec)
- Serum Magnesium - Guo G, Zhou J, Xu T, Sheng Z, Huang A, Sun L, Yao LEffect of Magnesium Supplementation on Chronic Kidney Disease-Mineral and Bone Disorder in Hemodialysis Patients: A Meta-Analysis of Randomized Controlled Trials.J Ren Nutr.(2022-Jan)
- Blood Pressure - Saba S, Faizi F, Sepandi M, Nehrir BEffect of short-term magnesium supplementation on anxiety, depression and sleep quality in patients after open-heart surgery.Magnes Res.(2022-Apr-01)
- Blood Pressure - Marques BCAA, Klein MRST, da Cunha MR, de Souza Mattos S, de Paula Nogueira L, de Paula T, Corrêa FM, Oigman W, Neves MFEffects of Oral Magnesium Supplementation on Vascular Function: A Systematic Review and Meta-analysis of Randomized Controlled Trials.High Blood Press Cardiovasc Prev.(2020-Feb)
- Fasting Glucose - Qu Q, Rong R, Yu JEffect of magnesium supplementation on pregnancy outcome in gestational diabetes mellitus patients: A meta-analysis of randomized controlled trials.Food Sci Nutr.(2022-Oct)
- Fasting Glucose - Xiaoqing Tan, Yi HuangMagnesium supplementation for glycemic status in women with gestational diabetes: a systematic review and meta-analysisGynecol Endocrinol.(2021 Dec 15)
- Body Mass Index (BMI) - Askari M, Mozaffari H, Jafari A, Ghanbari M, Darooghegi Mofrad MThe effects of magnesium supplementation on obesity measures in adults: a systematic review and dose-response meta-analysis of randomized controlled trials.Crit Rev Food Sci Nutr.(2021)
ZINCO81 riferimenti
- PMS Symptoms - Jafari F, Amani R, Tarrahi MJEffect of Zinc Supplementation on Physical and Psychological Symptoms, Biomarkers of Inflammation, Oxidative Stress, and Brain-Derived Neurotrophic Factor in Young Women with Premenstrual Syndrome: a Randomized, Double-Blind, Placebo-Controlled TrialBiol Trace Elem Res.(2019 Jun 2)
- PMS Symptoms - Siahbazi S, Behboudi-Gandevani S, Moghaddam-Banaem L, Montazeri AEffect of zinc sulfate supplementation on premenstrual syndrome and health-related quality of life: Clinical randomized controlled trialJ Obstet Gynaecol Res.(2017 May)
- Apolipoprotein A - Kelishadi R, Hashemipour M, Adeli K, Tavakoli N, Movahedian-Attar A, Shapouri J, Poursafa P, Rouzbahani AEffect of zinc supplementation on markers of insulin resistance, oxidative stress, and inflammation among prepubescent children with metabolic syndromeMetab Syndr Relat Disord.(2010 Dec)
- Cell Adhesion Factors - Bao B, Prasad AS, Beck FW, Fitzgerald JT, Snell D, Bao GW, Singh T, Cardozo LJZinc decreases C-reactive protein, lipid peroxidation, and inflammatory cytokines in elderly subjects: a potential implication of zinc as an atheroprotective agentAm J Clin Nutr.(2010 Jun)
- Iron Absorption - Olivares M, Pizarro F, Ruz MNew insights about iron bioavailability inhibition by zincNutrition.(2007 Apr)
- Testosterone - Kilic MEffect of fatiguing bicycle exercise on thyroid hormone and testosterone levels in sedentary males supplemented with oral zincNeuro Endocrinol Lett.(2007 Oct)
- Rosacea Symptoms - Bamford JT, Gessert CE, Haller IV, Kruger K, Johnson BPRandomized, double-blind trial of 220 mg zinc sulfate twice daily in the treatment of rosaceaInt J Dermatol.(2012 Apr)
- Rosacea Symptoms - Sharquie KE, Najim RA, Al-Salman HNOral zinc sulfate in the treatment of rosacea: a double-blind, placebo-controlled studyInt J Dermatol.(2006 Jul)
- Upper Respiratory Tract Infection Symptoms - Al-Nakib W, Higgins PG, Barrow I, Batstone G, Tyrrell DAProphylaxis and treatment of rhinovirus colds with zinc gluconate lozengesJ Antimicrob Chemother.(1987 Dec)
- Upper Respiratory Tract Infection Symptoms - Hemilä HZinc lozenges and the common cold: a meta-analysis comparing zinc acetate and zinc gluconate, and the role of zinc dosageJRSM Open.(2017 May 2)
- Upper Respiratory Tract Infection Symptoms - Petrus E, Lawson K, Bucci L, Blum KRandomized, double-masked, placebo-controlled clinical study of the effectiveness of zinc acetate lozenges on common cold symptoms in allergy-tested subjectsCurr Ther Res.()
- Upper Respiratory Tract Infection Symptoms - Farr BM, Conner EM, Betts RF, Oleske J, Minnefor A, Gwaltney JM JrTwo randomized controlled trials of zinc gluconate lozenge therapy of experimentally induced rhinovirus coldsAntimicrob Agents Chemother.(1987 Aug)
- Upper Respiratory Tract Infection Symptoms - Godfrey JC, Conant Sloane B, Smith DS, Turco JH, Mercer N, Godfrey NJZinc gluconate and the common cold: a controlled clinical studyJ Int Med Res.(1992 Jun)
- Upper Respiratory Tract Infection Symptoms - Prasad AS, Beck FW, Bao B, Snell D, Fitzgerald JTDuration and severity of symptoms and levels of plasma interleukin-1 receptor antagonist, soluble tumor necrosis factor receptor, and adhesion molecules in patients with common cold treated with zinc acetateJ Infect Dis.(2008 Mar 15)
- Upper Respiratory Tract Infection Symptoms - Hemilä H, Haukka J, Alho M, Vahtera J, Kivimäki MZinc acetate lozenges for the treatment of the common cold: a randomised controlled trialBMJ Open.(2020 Jan 23)
- Upper Respiratory Tract Infection Symptoms - Mossad SB, Macknin ML, Medendorp SV, Mason PZinc gluconate lozenges for treating the common cold. A randomized, double-blind, placebo-controlled studyAnn Intern Med.(1996 Jul 15)
- Upper Respiratory Tract Infection Symptoms - Turner RB, Cetnarowski WEEffect of treatment with zinc gluconate or zinc acetate on experimental and natural coldsClin Infect Dis.(2000 Nov)
- Upper Respiratory Tract Infection Symptoms - Eby GA, Davis DR, Halcomb WWReduction in duration of common colds by zinc gluconate lozenges in a double-blind studyAntimicrob Agents Chemother.(1984 Jan)
- Upper Respiratory Tract Infection Symptoms - Weismann K, Jakobsen JP, Weismann JE, Hammer UM, Nyholm SM, Hansen B, Lomholt KE, Schmidt KZinc gluconate lozenges for common cold. A double-blind clinical trialDan Med Bull.(1990 Jun)
- Upper Respiratory Tract Infection Symptoms - Prasad AS, Fitzgerald JT, Bao B, Beck FW, Chandrasekar PHDuration of symptoms and plasma cytokine levels in patients with the common cold treated with zinc acetate. A randomized, double-blind, placebo-controlled trialAnn Intern Med.(2000 Aug 15)
- Upper Respiratory Tract Infection Risk - Prasad AS, Beck FW, Bao B, Fitzgerald JT, Snell DC, Steinberg JD, Cardozo LJZinc supplementation decreases incidence of infections in the elderly: effect of zinc on generation of cytokines and oxidative stressAm J Clin Nutr.(2007 Mar)
- Mucositis Symptoms - Ertekin MV, Koç M, Karslioglu I, Sezen OZinc sulfate in the prevention of radiation-induced oropharyngeal mucositis: a prospective, placebo-controlled, randomized studyInt J Radiat Oncol Biol Phys.(2004 Jan 1)
- IGF-1 - Rodondi A, Ammann P, Ghilardi-Beuret S, Rizzoli RZinc increases the effects of essential amino acids-whey protein supplements in frail elderlyJ Nutr Health Aging.(2009 Jun)
- Serum BDNF - Ranjbar E, Shams J, Sabetkasaei M, M-Shirazi M, Rashidkhani B, Mostafavi A, Bornak E, Nasrollahzadeh JEffects of zinc supplementation on efficacy of antidepressant therapy, inflammatory cytokines, and brain-derived neurotrophic factor in patients with major depressionNutr Neurosci.(2014 Feb)
- Serum BDNF - Solati Z, Jazayeri S, Tehrani-Doost M, Mahmoodianfard S, Gohari MRZinc monotherapy increases serum brain-derived neurotrophic factor (BDNF) levels and decreases depressive symptoms in overweight or obese subjects: A double-blind, randomized, placebo-controlled trialNutr Neurosci.(2014 Jan 7)
- Depression Symptoms - Sawada T, Yokoi KEffect of zinc supplementation on mood states in young women: a pilot studyEur J Clin Nutr.(2010 Mar)
- Depression Symptoms - Siwek M, Dudek D, Paul IA, Sowa-Kućma M, Zieba A, Popik P, Pilc A, Nowak GZinc supplementation augments efficacy of imipramine in treatment resistant patients: a double blind, placebo-controlled studyJ Affect Disord.(2009 Nov)
- Reaction Time - Tupe RP, Chiplonkar SAZinc supplementation improved cognitive performance and taste acuity in Indian adolescent girlsJ Am Coll Nutr.(2009 Aug)
- DHT - Netter A, Hartoma R, Nahoul KEffect of zinc administration on plasma testosterone, dihydrotestosterone, and sperm countArch Androl.(1981 Aug)
- IGF-1 - Blostein-Fujii A, DiSilvestro RA, Frid D, Katz C, Malarkey WShort-term zinc supplementation in women with non-insulin-dependent diabetes mellitus: effects on plasma 5'-nucleotidase activities, insulin-like growth factor I concentrations, and lipoprotein oxidation rates in vitroAm J Clin Nutr.(1997 Sep)
- Glycemic Control - Ghaedi K, Ghasempour D, Jowshan M, Zheng M, Ghobadi S, Jafari AEffect of zinc supplementation in the management of type 2 diabetes: A grading of recommendations assessment, development, and evaluation-assessed, dose-response meta-analysis of randomized controlled trials.Crit Rev Food Sci Nutr.(2023-May-15)
- Fasting Glucose - Laura M Pompano, Erick BoyEffects of Dose and Duration of Zinc Interventions on Risk Factors for Type 2 Diabetes and Cardiovascular Disease: A Systematic Review and Meta-AnalysisAdv Nutr.(2020 Jul 28)
- Total cholesterol - Asbaghi O, Sadeghian M, Fouladvand F, Panahande B, Nasiri M, Khodadost M, Shokri A, Pirouzi A, Sadeghi OEffects of zinc supplementation on lipid profile in patients with type 2 diabetes mellitus: A systematic review and meta-analysis of randomized controlled trials.Nutr Metab Cardiovasc Dis.(2020-Jul-24)
- Insulin - Hashemipour M, Kelishadi R, Shapouri J, Sarrafzadegan N, Amini M, Tavakoli N, Movahedian-Attar A, Mirmoghtadaee P, Poursafa PEffect of zinc supplementation on insulin resistance and components of the metabolic syndrome in prepubertal obese childrenHormones (Athens).(2009 Oct-Dec)
- Anti-Oxidant Enzyme Profile - Kara E, Gunay M, Cicioglu I, Ozal M, Kilic M, Mogulkoc R, Baltaci AKEffect of zinc supplementation on antioxidant activity in young wrestlersBiol Trace Elem Res.(2010 Apr)
- General Oxidation - Seet RC, Lee CY, Lim EC, Quek AM, Huang H, Huang SH, Looi WF, Long LH, Halliwell BOral zinc supplementation does not improve oxidative stress or vascular function in patients with type 2 diabetes with normal zinc levelsAtherosclerosis.(2011 Nov)
- Body Fat - C S Mantzoros, A S Prasad, F W Beck, S Grabowski, J Kaplan, C Adair, G J BrewerZinc may regulate serum leptin concentrations in humansJ Am Coll Nutr.(1998 Jun)
- Wart Severity - Al-Gurairi FT, Al-Waiz M, Sharquie KEOral zinc sulphate in the treatment of recalcitrant viral warts: randomized placebo-controlled clinical trialBr J Dermatol.(2002 Mar)
- Wart Severity - Sharquie KE, Khorsheed AA, Al-Nuaimy AATopical zinc sulphate solution for treatment of viral wartsSaudi Med J.(2007 Sep)
- Wart Severity - Mun JH, Kim SH, Jung DS, Ko HC, Kim BS, Kwon KS, Kim MBOral zinc sulfate treatment for viral warts: an open-label studyJ Dermatol.(2011 Jun)
- Pneumonia Symptoms - Valavi E, Hakimzadeh M, Shamsizadeh A, Aminzadeh M, Alghasi AThe efficacy of zinc supplementation on outcome of children with severe pneumonia. A randomized double-blind placebo-controlled clinical trialIndian J Pediatr.(2011 Sep)
- Pneumonia Symptoms - Wadhwa N, Chandran A, Aneja S, Lodha R, Kabra SK, Chaturvedi MK, Sodhi J, Fitzwater SP, Chandra J, Rath B, Kainth US, Saini S, Black RE, Santosham M, Bhatnagar SEfficacy of zinc given as an adjunct in the treatment of severe and very severe pneumonia in hospitalized children 2-24 mo of age: a randomized, double-blind, placebo-controlled trialAm J Clin Nutr.(2013 Jun)
- Pneumonia Symptoms - Chandyo RK, Shrestha PS, Valentiner-Branth P, Mathisen M, Basnet S, Ulak M, Adhikari RK, Sommerfelt H, Strand TATwo weeks of zinc administration to Nepalese children with pneumonia does not reduce the incidence of pneumonia or diarrhea during the next six monthsJ Nutr.(2010 Sep)
- Pneumonia Symptoms - Shah GS, Dutta AK, Shah D, Mishra OPRole of zinc in severe pneumonia: a randomized double bind placebo controlled studyItal J Pediatr.(2012 Aug 2)
- Pneumonia Symptoms - Ganguly A, Chakraborty S, Datta K, Hazra A, Datta S, Chakraborty JA randomized controlled trial of oral zinc in acute pneumonia in children aged between 2 months to 5 yearsIndian J Pediatr.(2011 Sep)
- Pneumonia Symptoms - Srinivasan MG, Ndeezi G, Mboijana CK, Kiguli S, Bimenya GS, Nankabirwa V, Tumwine JKZinc adjunct therapy reduces case fatality in severe childhood pneumonia: a randomized double blind placebo-controlled trialBMC Med.(2012 Feb 8)
- Pneumonia Symptoms - Valentiner-Branth P, Shrestha PS, Chandyo RK, Mathisen M, Basnet S, Bhandari N, Adhikari RK, Sommerfelt H, Strand TAA randomized controlled trial of the effect of zinc as adjuvant therapy in children 2-35 mo of age with severe or nonsevere pneumonia in Bhaktapur, NepalAm J Clin Nutr.(2010 Jun)
- Pneumonia Symptoms - Basnet S, Shrestha PS, Sharma A, Mathisen M, Prasai R, Bhandari N, Adhikari RK, Sommerfelt H, Valentiner-Branth P, Strand TA; Zinc Severe Pneumonia Study GroupA randomized controlled trial of zinc as adjuvant therapy for severe pneumonia in young childrenPediatrics.(2012 Apr)
- Cognition - Aquilani R, Baiardi P, Scocchi M, Iadarola P, Verri M, Sessarego P, Boschi F, Pasini E, Pastoris O, Viglio SNormalization of zinc intake enhances neurological retrieval of patients suffering from ischemic strokesNutr Neurosci.(2009 Oct)
- Tinnitus Symptoms - Arda HN, Tuncel U, Akdogan O, Ozluoglu LNThe role of zinc in the treatment of tinnitusOtol Neurotol.(2003 Jan)
- Testosterone - Kilic M, Baltaci AK, Gunay M, Gökbel H, Okudan N, Cicioglu IThe effect of exhaustion exercise on thyroid hormones and testosterone levels of elite athletes receiving oral zincNeuro Endocrinol Lett.(2006 Feb-Apr)
- Acne Symptoms - Dreno B, Moyse D, Alirezai M, Amblard P, Auffret N, Beylot C, Bodokh I, Chivot M, Daniel F, Humbert P, Meynadier J, Poli F; Acne Research and Study GroupMulticenter randomized comparative double-blind controlled clinical trial of the safety and efficacy of zinc gluconate versus minocycline hydrochloride in the treatment of inflammatory acne vulgarisDermatology.(2001)
- Acne Symptoms - Verma KC, Saini AS, Dhamija SKOral zinc sulphate therapy in acne vulgaris: a double-blind trialActa Derm Venereol.(1980)
- Acne Symptoms - Dreno B, Amblard P, Agache P, Sirot S, Litoux PLow doses of zinc gluconate for inflammatory acneActa Derm Venereol.(1989)
- Acne Symptoms - Göransson K, Lidén S, Odsell LOral zinc in acne vulgaris: a clinical and methodological studyActa Derm Venereol.(1978)
- Acne Symptoms - Brittany E Yee, Phillip Richards, Jennifer Y Sui, Amanda Fleming MarschSerum zinc levels and efficacy of zinc treatment in acne vulgaris: A systematic review and meta-analysisDermatol Ther.(2020 Aug 29)
- Upper Respiratory Tract Infection Symptoms - Smith DS, Helzner EC, Nuttall CE Jr, Collins M, Rofman BA, Ginsberg D, Goswick CB, Magner AFailure of zinc gluconate in treatment of acute upper respiratory tract infectionsAntimicrob Agents Chemother.(1989 May)
- Iron Absorption - J K Friel, R E Serfass, P V Fennessey, L V Miller, W L Andrews, B S Simmons, G F Downton, P G KwaElevated intakes of zinc in infant formulas don not interfere with iron absorption in premature infantsJ Pediatr Gastroenterol Nutr.(1998 Sep)
- Spontaneous Birth Risk - Carducci B, Keats EC, Bhutta ZAZinc supplementation for improving pregnancy and infant outcome.Cochrane Database Syst Rev.(2021-Mar-16)
- Infant Growth - Lassi ZS, Kurji J, Oliveira CS, Moin A, Bhutta ZAZinc supplementation for the promotion of growth and prevention of infections in infants less than six months of age.Cochrane Database Syst Rev.(2020-Apr-08)
- Infant Growth - Belal Alshaikh, Moaaz Abo Zeed, Kamran Yusuf, Madhusudan Guin, Tanis FentonEffect of enteral zinc supplementation on growth and neurodevelopment of preterm infants: a systematic review and meta-analysisJ Perinatol.(2021 May 18)
- Cirrhosis Severity - Somi MH, Rezaeifar P, Ostad Rahimi A, Moshrefi BEffects of low dose zinc supplementation on biochemical markers in non-alcoholic cirrhosis: a randomized clinical trialArch Iran Med.(2012 Aug)
- Mucositis Symptoms - Mansouri A, Hadjibabaie M, Iravani M, Shamshiri AR, Hayatshahi A, Javadi MR, Khoee SH, Alimoghaddam K, Ghavamzadeh AThe effect of zinc sulfate in the prevention of high-dose chemotherapy-induced mucositis: a double-blind, randomized, placebo-controlled studyHematol Oncol.(2012 Mar)
- Psoriasis Symptoms - Sadeghian G, Ziaei H, Nilforoushzadeh MATreatment of localized psoriasis with a topical formulation of zinc pyrithioneActa Dermatovenerol Alp Panonica Adriat.(2011)
- Subjective Well-Being - Stewart-Knox BJ, Rae G, Simpson EE, McConville C, O'Connor J, Polito A, Andriollo-Sanchez M, Coudray C, Strain JJSupplemented zinc does not alter mood in healthy older European adults--a randomised placebo-controlled trial: the Zenith studyPublic Health Nutr.(2011 May)
- Testosterone - Ghanbarali Raeis Jalali, Jamshid Roozbeh, Azam Mohammadzadeh, Maryam Sharifian, Mohammad Mahdi Sagheb, Alireza Hamidian Jahromi, Sanaz Shabani, Fariborz Ghaffarpasand, Raha AfsharianiImpact of oral zinc therapy on the level of sex hormones in male patients on hemodialysisRen Fail.(2010 May)
- C-Reactive Protein (CRP) - Rashidi AA, Salehi M, Piroozmand A, Sagheb MMEffects of zinc supplementation on serum zinc and C-reactive protein concentrations in hemodialysis patientsJ Ren Nutr.(2009 Nov)
- ADHD Symptoms - Arnold LE, Disilvestro RA, Bozzolo D, Bozzolo H, Crowl L, Fernandez S, Ramadan Y, Thompson S, Mo X, Abdel-Rasoul M, Joseph EZinc for attention-deficit/hyperactivity disorder: placebo-controlled double-blind pilot trial alone and combined with amphetamineJ Child Adolesc Psychopharmacol.(2011 Feb)
- ADHD Symptoms - Talebi S, Miraghajani M, Ghavami A, Mohammadi HThe effect of zinc supplementation in children with attention deficit hyperactivity disorder: A systematic review and dose-response meta‑analysis of randomized clinical trials.Crit Rev Food Sci Nutr.(2022)
- Mucositis Symptoms - Sangthawan D, Phungrassami T, Sinkitjarurnchai WA randomized double-blind, placebo-controlled trial of zinc sulfate supplementation for alleviation of radiation-induced oral mucositis and pharyngitis in head and neck cancer patientsJ Med Assoc Thai.(2013 Jan)
- Mucositis Symptoms - Arbabi-kalati F, Arbabi-kalati F, Deghatipour M, Ansari Moghadam AEvaluation of the efficacy of zinc sulfate in the prevention of chemotherapy-induced mucositis: a double-blind randomized clinical trialArch Iran Med.(2012 Jul)
- OCD Symptoms - Sayyah M, Olapour A, Saeedabad Ys, Yazdan Parast R, Malayeri AEvaluation of oral zinc sulfate effect on obsessive-compulsive disorder: a randomized placebo-controlled clinical trialNutrition.(2012 Sep)
- Dysgeusia - Lyckholm L, Heddinger SP, Parker G, Coyne PJ, Ramakrishnan V, Smith TJ, Henkin RIA randomized, placebo controlled trial of oral zinc for chemotherapy-related taste and smell disordersJ Pain Palliat Care Pharmacother.(2012 Jun)
- Dental Health Metrics - Uçkardeş Y, Tekçiçek M, Ozmert EN, Yurdakök KThe effect of systemic zinc supplementation on oral health in low socioeconomic level childrenTurk J Pediatr.(2009 Sep-Oct)
- Itching - Najafabadi MM, Faghihi G, Emami A, Monghad M, Moeenzadeh F, Sharif N, Davarpanah Jazi AHZinc sulfate for relief of pruritus in patients on maintenance hemodialysisTher Apher Dial.(2012 Apr)
- Dysgeusia - R I Henkin, B M Martin, R P AgarwalEfficacy of exogenous oral zinc in treatment of patients with carbonic anhydrase VI deficiencyAm J Med Sci.(1999 Dec)
- Iron Absorption - Olivares M, Pizarro F, Ruz MZinc inhibits nonheme iron bioavailability in humansBiol Trace Elem Res.(2007 Summer)
- Iron Absorption - Olivares M, Wiedeman A, Bolívar L, López de Romaña D, Pizarro FEffect of increasing concentrations of zinc on the absorption of iron from iron-fortified milkBiol Trace Elem Res.(2012 Dec)
- Diarrhea Symptoms - Lazzerini M, Wanzira HOral zinc for treating diarrhoea in children.Cochrane Database Syst Rev.(2016-Dec-20)
- Diarrhea Symptoms - Lamberti LM, Walker CL, Chan KY, Jian WY, Black REOral zinc supplementation for the treatment of acute diarrhea in children: a systematic review and meta-analysis.Nutrients.(2013-Nov-21)
- Diarrhea Symptoms - Galvao TF, Thees MF, Pontes RF, Silva MT, Pereira MGZinc supplementation for treating diarrhea in children: a systematic review and meta-analysis.Rev Panam Salud Publica.(2013-May)
VITAMINA D98 riferimenti
- Asif A, Farooq NVitamin D ToxicityStatPearls.(2023-01)
- Bischoff-Ferrari HA, Dawson-Hughes B, Orav EJ, Staehelin HB, Meyer OW, Theiler R, Dick W, Willett WC, Egli AMonthly High-Dose Vitamin D Treatment for the Prevention of Functional Decline: A Randomized Clinical TrialJAMA Intern Med.(2016 Feb)
- Lawrence J Appel, Erin D Michos, Christine M Mitchell, Amanda L Blackford, Alice L Sternberg, Edgar R Miller 3rd, Stephen P Juraschek, Jennifer A Schrack, Sarah L Szanton, Jeanne Charleston, Melissa Minotti, Sheriza N Baksh, Robert H Christenson, Josef Coresh, Lea T Drye, Jack M Guralnik, Rita R Kalyani, Timothy B Plante, David M Shade, David L Roth, James Tonascia, STURDY Collaborative Research GroupThe Effects of Four Doses of Vitamin D Supplements on Falls in Older Adults : A Response-Adaptive, Randomized Clinical TrialAnn Intern Med.(2021 Feb)
- Lauren A Burt, Emma O Billington, Marianne S Rose, Richard Kremer, David A Hanley, Steven K BoydAdverse Effects of High-Dose Vitamin D Supplementation on Volumetric Bone Density Are Greater in Females than MalesJ Bone Miner Res.(2020 Dec)
- Maestro MA, Molnár F, Mouriño A, Carlberg CVitamin D receptor 2016: novel ligands and structural insights.Expert Opin Ther Pat.(2016-Nov)
- Zmijewski MA, Carlberg CVitamin D receptor(s): In the nucleus but also at membranes?Exp Dermatol.(2020-Sep)
- Carlberg CVitamin D and Its Target Genes.Nutrients.(2022-Mar-24)
- Wang W, Li Y, Meng XVitamin D and neurodegenerative diseases.Heliyon.(2023-Jan)
- Eyles DW, Burne TH, McGrath JJVitamin D, effects on brain development, adult brain function and the links between low levels of vitamin D and neuropsychiatric disease.Front Neuroendocrinol.(2013-Jan)
- Fernandes de Abreu DA, Eyles D, Féron FVitamin D, a neuro-immunomodulator: implications for neurodegenerative and autoimmune diseases.Psychoneuroendocrinology.(2009-Dec)
- Chen S, Sims GP, Chen XX, Gu YY, Chen S, Lipsky PEModulatory effects of 1,25-dihydroxyvitamin D3 on human B cell differentiation.J Immunol.(2007-Aug-01)
- Ma Y, Johnson CS, Trump DLMechanistic Insights of Vitamin D Anticancer Effects.Vitam Horm.(2016)
- Chen L, Yang R, Qiao W, Zhang W, Chen J, Mao L, Goltzman D, Miao D1,25-Dihydroxyvitamin D exerts an antiaging role by activation of Nrf2-antioxidant signaling and inactivation of p16/p53-senescence signaling.Aging Cell.(2019-Jun)
- Prietl B, Treiber G, Pieber TR, Amrein KVitamin D and immune functionNutrients.(2013 Jul 5)
- Enkhjargal B, Malaguit J, Ho WM, Jiang W, Wan W, Wang G, Tang J, Zhang JHVitamin D attenuates cerebral artery remodeling through VDR/AMPK/eNOS dimer phosphorylation pathway after subarachnoid hemorrhage in rats.J Cereb Blood Flow Metab.(2019-Feb)
- Nair R, Maseeh AVitamin D: The "sunshine" vitaminJ Pharmacol Pharmacother.(2012 Apr)
- Parker GB, Brotchie H, Graham RKVitamin D and depressionJ Affect Disord.(2017 Jan 15)
- Allan GM, Cranston L, Lindblad A, McCormack J, Kolber MR, Garrison S, Korownyk CVitamin D: A Narrative Review Examining the Evidence for Ten BeliefsJ Gen Intern Med.(2016 Jul)
- Gowda U, Mutowo MP, Smith BJ, Wluka AE, Renzaho AMVitamin D supplementation to reduce depression in adults: meta-analysis of randomized controlled trialsNutrition.(2015 Mar)
- Spedding SVitamin D and depression: a systematic review and meta-analysis comparing studies with and without biological flawsNutrients.(2014 Apr 11)
- F Vellekkatt, V MenonEfficacy of vitamin D supplementation in major depression: A meta-analysis of randomized controlled trialsJ Postgrad Med.(Apr-Jun 2019)
- Vaziri F, Nasiri S, Tavana Z, Dabbaghmanesh MH, Sharif F, Jafari PA randomized controlled trial of vitamin D supplementation on perinatal depression: in Iranian pregnant mothersBMC Pregnancy Childbirth.(2016 Aug 20)
- Pilz S, Frisch S, Koertke H, Kuhn J, Dreier J, Obermayer-Pietsch B, Wehr E, Zittermann AEffect of vitamin D supplementation on testosterone levels in menHorm Metab Res.(2011 Mar)
- Wehr E, Pilz S, Boehm BO, März W, Obermayer-Pietsch BAssociation of vitamin D status with serum androgen levels in menClin Endocrinol (Oxf).(2010 Aug)
- Rodgers S, Grosse Holtforth M, Hengartner MP, Müller M, Aleksandrowicz AA, Rössler W, Ajdacic-Gross VSerum testosterone levels and symptom-based depression subtypes in menFront Psychiatry.(2015 May 4)
- Johnson JM, Nachtigall LB, Stern TAThe effect of testosterone levels on mood in men: a reviewPsychosomatics.(2013 Nov-Dec)
- Bassil N, Alkaade S, Morley JEThe benefits and risks of testosterone replacement therapy: a reviewTher Clin Risk Manag.(2009 Jun)
- Zarrouf FA, Artz S, Griffith J, Sirbu C, Kommor MTestosterone and depression: systematic review and meta-analysisJ Psychiatr Pract.(2009 Jul)
- Davis SR, Wahlin-Jacobsen STestosterone in women--the clinical significanceLancet Diabetes Endocrinol.(2015 Dec)
- Sharma A, Madaan V, Petty FDExercise for mental healthPrim Care Companion J Clin Psychiatry.(2006)
- Melrose SSeasonal Affective Disorder: An Overview of Assessment and Treatment ApproachesDepress Res Treat.(2015)
- O'Hare C, O'Sullivan V, Flood S, Kenny RASeasonal and meteorological associations with depressive symptoms in older adults: A geo-epidemiological studyJ Affect Disord.(2016 Feb)
- Golden RN, Gaynes BN, Ekstrom RD, Hamer RM, Jacobsen FM, Suppes T, Wisner KL, Nemeroff CBThe efficacy of light therapy in the treatment of mood disorders: a review and meta-analysis of the evidenceAm J Psychiatry.(2005 Apr)
- Lam RW, Levitt AJ, Levitan RD, Enns MW, Morehouse R, Michalak EE, Tam EMThe Can-SAD study: a randomized controlled trial of the effectiveness of light therapy and fluoxetine in patients with winter seasonal affective disorderAm J Psychiatry.(2006 May)
- Kerr DC, Zava DT, Piper WT, Saturn SR, Frei B, Gombart AFAssociations between vitamin D levels and depressive symptoms in healthy young adult womenPsychiatry Res.(2015 May 30)
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VITAMINA K73 riferimenti
- Dam HThe antihaemorrhagic vitamin of the chickBiochem J.(1935 Jun)
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- Garber AK, Binkley NC, Krueger DC, Suttie JWComparison of phylloquinone bioavailability from food sources or a supplement in human subjectsJ Nutr.(1999 Jun)
- Gijsbers BL, Jie KS, Vermeer CEffect of food composition on vitamin K absorption in human volunteersBr J Nutr.(1996 Aug)
- Ageno W, Gallus AS, Wittkowsky A, Crowther M, Hylek EM, Palareti GOral anticoagulant therapy: Antithrombotic Therapy and Prevention of Thrombosis, 9th ed: American College of Chest Physicians Evidence-Based Clinical Practice GuidelinesChest.(2012 Feb)
- Booth SLVitamin K: food composition and dietary intakesFood Nutr Res.(2012)
- Kurosu M, Begari EVitamin K2 in electron transport system: are enzymes involved in vitamin K2 biosynthesis promising drug targets?Molecules.(2010 Mar 10)
- Shearer MJ, Newman PMetabolism and cell biology of vitamin KThromb Haemost.(2008 Oct)
- Davidson RT, Foley AL, Engelke JA, Suttie JWConversion of dietary phylloquinone to tissue menaquinone-4 in rats is not dependent on gut bacteriaJ Nutr.(1998 Feb)
- Ronden JE, Drittij-Reijnders MJ, Vermeer C, Thijssen HHIntestinal flora is not an intermediate in the phylloquinone-menaquinone-4 conversion in the ratBiochim Biophys Acta.(1998 Jan 8)
- Beulens JW, Booth SL, van den Heuvel EG, Stoecklin E, Baka A, Vermeer CThe role of menaquinones (vitamin K₂) in human healthBr J Nutr.(2013 Oct)
- Miggiano GA, Robilotta LVitamin K-controlled diet: problems and prospectsClin Ter.(2005 Jan-Apr)
- Ichihashi T, Takagishi Y, Uchida K, Yamada HColonic absorption of menaquinone-4 and menaquinone-9 in ratsJ Nutr.(1992 Mar)
- Holmes MV, Hunt BJ, Shearer MJThe role of dietary vitamin K in the management of oral vitamin K antagonistsBlood Rev.(2012 Jan)
- Ikeda Y, Iki M, Morita A, Kajita E, Kagamimori S, Kagawa Y, Yoneshima HIntake of fermented soybeans, natto, is associated with reduced bone loss in postmenopausal women: Japanese Population-Based Osteoporosis (JPOS) StudyJ Nutr.(2006 May)
- Katsuyama H, Ideguchi S, Fukunaga M, Saijoh K, Sunami SUsual dietary intake of fermented soybeans (Natto) is associated with bone mineral density in premenopausal womenJ Nutr Sci Vitaminol (Tokyo).(2002 Jun)
- Sato T, Schurgers LJ, Uenishi KComparison of menaquinone-4 and menaquinone-7 bioavailability in healthy womenNutr J.(2012 Nov 12)
- Vermeer CVitamin K: the effect on health beyond coagulation - an overviewFood Nutr Res.(2012)
- Schurgers LJ, Teunissen KJ, Hamulyák K, Knapen MH, Vik H, Vermeer CVitamin K-containing dietary supplements: comparison of synthetic vitamin K1 and natto-derived menaquinone-7Blood.(2007 Apr 15)
- Schurgers LJ, Vermeer CDifferential lipoprotein transport pathways of K-vitamins in healthy subjectsBiochim Biophys Acta.(2002 Feb 15)
- Schurgers LJ, Vermeer CDetermination of phylloquinone and menaquinones in food. Effect of food matrix on circulating vitamin K concentrationsHaemostasis.(2000 Nov-Dec)
- Nakagawa K, Hirota Y, Sawada N, Yuge N, Watanabe M, Uchino Y, Okuda N, Shimomura Y, Suhara Y, Okano TIdentification of UBIAD1 as a novel human menaquinone-4 biosynthetic enzymeNature.(2010 Nov 4)
- Shearer MJVitamin KLancet.(1995 Jan 28)
- American Academy of Pediatrics Committee on Fetus and NewbornControversies concerning vitamin K and the newborn. American Academy of Pediatrics Committee on Fetus and NewbornPediatrics.(2003 Jul)
- Spronk HM, Soute BA, Schurgers LJ, Thijssen HH, De Mey JG, Vermeer CTissue-specific utilization of menaquinone-4 results in the prevention of arterial calcification in warfarin-treated ratsJ Vasc Res.(2003 Nov-Dec)
- Groenen-van Dooren MM, Soute BA, Jie KS, Thijssen HH, Vermeer CThe relative effects of phylloquinone and menaquinone-4 on the blood coagulation factor synthesis in vitamin K-deficient ratsBiochem Pharmacol.(1993 Aug 3)
- Theuwissen E, Teunissen KJ, Spronk HM, Hamulyák K, Ten Cate H, Shearer MJ, Vermeer C, Schurgers LJEffect of low-dose supplements of menaquinone-7 (vitamin K2 ) on the stability of oral anticoagulant treatment: dose-response relationship in healthy volunteersJ Thromb Haemost.(2013 Jun)
- Schurgers LJ, Shearer MJ, Hamulyák K, Stöcklin E, Vermeer CEffect of vitamin K intake on the stability of oral anticoagulant treatment: dose-response relationships in healthy subjectsBlood.(2004 Nov 1)
- Ushiroyama T, Ikeda A, Ueki MEffect of continuous combined therapy with vitamin K(2) and vitamin D(3) on bone mineral density and coagulofibrinolysis function in postmenopausal womenMaturitas.(2002 Mar 25)
- Asakura H, Myou S, Ontachi Y, Mizutani T, Kato M, Saito M, Morishita E, Yamazaki M, Nakao SVitamin K administration to elderly patients with osteoporosis induces no hemostatic activation, even in those with suspected vitamin K deficiencyOsteoporos Int.(2001 Dec)
- Mayer O Jr, Seidlerová J, Bruthans J, Filipovský J, Timoracká K, Vaněk J, Cerná L, Wohlfahrt P, Cífková R, Theuwissen E, Vermeer CDesphospho-uncarboxylated matrix Gla-protein is associated with mortality risk in patients with chronic stable vascular diseaseAtherosclerosis.(2014 Jul)
- Chatrou ML, Winckers K, Hackeng TM, Reutelingsperger CP, Schurgers LJVascular calcification: the price to pay for anticoagulation therapy with vitamin K-antagonistsBlood Rev.(2012 Jul)
- Gast GC, de Roos NM, Sluijs I, Bots ML, Beulens JW, Geleijnse JM, Witteman JC, Grobbee DE, Peeters PH, van der Schouw YTA high menaquinone intake reduces the incidence of coronary heart diseaseNutr Metab Cardiovasc Dis.(2009 Sep)
- Beulens JW, Bots ML, Atsma F, Bartelink ML, Prokop M, Geleijnse JM, Witteman JC, Grobbee DE, van der Schouw YTHigh dietary menaquinone intake is associated with reduced coronary calcificationAtherosclerosis.(2009 Apr)
- Geleijnse JM, Vermeer C, Grobbee DE, Schurgers LJ, Knapen MH, van der Meer IM, Hofman A, Witteman JCDietary intake of menaquinone is associated with a reduced risk of coronary heart disease: the Rotterdam StudyJ Nutr.(2004 Nov)
- El Asmar MS, Naoum JJ, Arbid EJVitamin k dependent proteins and the role of vitamin k2 in the modulation of vascular calcification: a reviewOman Med J.(2014 May)
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- Braam LA, Hoeks AP, Brouns F, Hamulyák K, Gerichhausen MJ, Vermeer CBeneficial effects of vitamins D and K on the elastic properties of the vessel wall in postmenopausal women: a follow-up studyThromb Haemost.(2004 Feb)
- Kurnatowska I, Grzelak P, Masajtis-Zagajewska A, Kaczmarska M, Stefańczyk L, Vermeer C, Maresz K, Nowicki MEffect of vitamin K2 on progression of atherosclerosis and vascular calcification in nondialyzed patients with chronic kidney disease stages 3-5Pol Arch Med Wewn.(2015)
- Knapen MH, Braam LA, Drummen NE, Bekers O, Hoeks AP, Vermeer CMenaquinone-7 supplementation improves arterial stiffness in healthy postmenopausal women. A double-blind randomised clinical trialThromb Haemost.(2015 May)
- Fulton RL, McMurdo ME, Hill A, Abboud RJ, Arnold GP, Struthers AD, Khan F, Vermeer C, Knapen MH, Drummen NE, Witham MDEffect of Vitamin K on Vascular Health and Physical Function in Older People with Vascular Disease--A Randomised Controlled TrialJ Nutr Health Aging.(2016 Mar)
- Caraballo PJ, Heit JA, Atkinson EJ, Silverstein MD, O'Fallon WM, Castro MR, Melton LJ 3rdLong-term use of oral anticoagulants and the risk of fractureArch Intern Med.(1999 Aug 9-23)
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- Jamal SA, Browner WS, Bauer DC, Cummings SRWarfarin use and risk for osteoporosis in elderly women. Study of Osteoporotic Fractures Research GroupAnn Intern Med.(1998 May 15)
- Hodges SJ, Pilkington MJ, Shearer MJ, Bitensky L, Chayen JAge-related changes in the circulating levels of congeners of vitamin K2, menaquinone-7 and menaquinone-8Clin Sci (Lond).(1990 Jan)
- Pisani P, Renna MD, Conversano F, Casciaro E, Di Paola M, Quarta E, Muratore M, Casciaro SMajor osteoporotic fragility fractures: Risk factor updates and societal impactWorld J Orthop.(2016 Mar 18)
- Dhanwal DK, Dennison EM, Harvey NC, Cooper CEpidemiology of hip fracture: Worldwide geographic variationIndian J Orthop.(2011 Jan)
- Johnell O, Kanis JAAn estimate of the worldwide prevalence and disability associated with osteoporotic fracturesOsteoporos Int.(2006 Dec)
- Fang Y, Hu C, Tao X, Wan Y, Tao FEffect of vitamin K on bone mineral density: a meta-analysis of randomized controlled trialsJ Bone Miner Metab.(2012 Jan)
- Cockayne S, Adamson J, Lanham-New S, Shearer MJ, Gilbody S, Torgerson DJVitamin K and the prevention of fractures: systematic review and meta-analysis of randomized controlled trialsArch Intern Med.(2006 Jun 26)
- Cheung AM, Tile L, Lee Y, Tomlinson G, Hawker G, Scher J, Hu H, Vieth R, Thompson L, Jamal S, Josse RVitamin K supplementation in postmenopausal women with osteopenia (ECKO trial): a randomized controlled trialPLoS Med.(2008 Oct 14)
- Emaus N, Gjesdal CG, Almås B, Christensen M, Grimsgaard AS, Berntsen GK, Salomonsen L, Fønnebø VVitamin K2 supplementation does not influence bone loss in early menopausal women: a randomised double-blind placebo-controlled trialOsteoporos Int.(2010 Oct)
- Knapen MH, Drummen NE, Smit E, Vermeer C, Theuwissen EThree-year low-dose menaquinone-7 supplementation helps decrease bone loss in healthy postmenopausal womenOsteoporos Int.(2013 Sep)
- Sasaki N, Kusano E, Takahashi H, Ando Y, Yano K, Tsuda E, Asano YVitamin K2 inhibits glucocorticoid-induced bone loss partly by preventing the reduction of osteoprotegerin (OPG)J Bone Miner Metab.(2005)
- Koitaya N, Sekiguchi M, Tousen Y, Nishide Y, Morita A, Yamauchi J, Gando Y, Miyachi M, Aoki M, Komatsu M, Watanabe F, Morishita K, Ishimi YLow-dose vitamin K2 (MK-4) supplementation for 12 months improves bone metabolism and prevents forearm bone loss in postmenopausal Japanese womenJ Bone Miner Metab.(2013 May 24)
- Nowak JK, Grzybowska-Chlebowczyk U, Landowski P, Szaflarska-Poplawska A, Klincewicz B, Adamczak D, Banasiewicz T, Plawski A, Walkowiak JPrevalence and correlates of vitamin K deficiency in children with inflammatory bowel diseaseSci Rep.(2014 Apr 24)
- Jagannath VA, Fedorowicz Z, Thaker V, Chang ABVitamin K supplementation for cystic fibrosisCochrane Database Syst Rev.(2013 Apr 30)
- Nakajima S, Iijima H, Egawa S, Shinzaki S, Kondo J, Inoue T, Hayashi Y, Ying J, Mukai A, Akasaka T, Nishida T, Kanto T, Tsujii M, Hayashi NAssociation of vitamin K deficiency with bone metabolism and clinical disease activity in inflammatory bowel diseaseNutrition.(2011 Oct)
- Booth SL, Pennington JA, Sadowski JAFood sources and dietary intakes of vitamin K-1 (phylloquinone) in the American diet: data from the FDA Total Diet StudyJ Am Diet Assoc.(1996 Feb)
- Shiratori T, Sato A, Fukuzawa M, Kondo N, Tanno SSevere Dextran-Induced Anaphylactic Shock during Induction of Hypertension-Hypervolemia-Hemodilution Therapy following Subarachnoid HemorrhageCase Rep Crit Care.(2015)
- Riegert-Johnson DL, Volcheck GWThe incidence of anaphylaxis following intravenous phytonadione (vitamin K1): a 5-year retrospective reviewAnn Allergy Asthma Immunol.(2002 Oct)
- Bullen AW, Miller JP, Cunliffe WJ, Losowsky MSSkin reactions caused by vitamin K in patients with liver diseaseBr J Dermatol.(1978 May)
- Institute of Medicine (US) Panel on MicronutrientsDietary Reference Intakes for Vitamin A, Vitamin K, Arsenic, Boron, Chromium, Copper, Iodine, Iron, Manganese, Molybdenum, Nickel, Silicon, Vanadium, and Zinc
- Fu X, Shen X, Finnan EG, Haytowitz DB, Booth SLMeasurement of Multiple Vitamin K Forms in Processed and Fresh-Cut Pork Products in the U.S. Food SupplyJ Agric Food Chem.(2016 Jun 8)
- Manoury E, Jourdon K, Boyaval P, Fourcassié PQuantitative measurement of vitamin K2 (menaquinones) in various fermented dairy products using a reliable high-performance liquid chromatography methodJ Dairy Sci.(2013 Mar)
- Kamao M, Suhara Y, Tsugawa N, Uwano M, Yamaguchi N, Uenishi K, Ishida H, Sasaki S, Okano TVitamin K content of foods and dietary vitamin K intake in Japanese young womenJ Nutr Sci Vitaminol (Tokyo).(2007 Dec)
- Elder SJ, Haytowitz DB, Howe J, Peterson JW, Booth SLVitamin k contents of meat, dairy, and fast food in the u.s. DietJ Agric Food Chem.(2006 Jan 25)
- Shimogawara K, Muto SPurification of Chlamydomonas 28-kDa ubiquitinated protein and its identification as ubiquitinated histone H2BArch Biochem Biophys.(1992 Apr)
- Hirauchi K, Sakano T, Notsumoto S, Nagaoka T, Morimoto A, Fujimoto K, Masuda S, Suzuki YMeasurement of K vitamins in animal tissues by high-performance liquid chromatography with fluorimetric detectionJ Chromatogr.(1989 Dec 29)
- Chen GC, Wang Y, Tong X, Szeto IMY, Smit G, Li ZN, Qin LQCheese consumption and risk of cardiovascular disease: a meta-analysis of prospective studiesEur J Nutr.(2017 Dec)
- Villines TC, Hatzigeorgiou C, Feuerstein IM, O'Malley PG, Taylor AJVitamin K1 intake and coronary calcificationCoron Artery Dis.(2005 May)
- Hao G, Zhang B, Gu M, Chen C, Zhang Q, Zhang G, Cao XVitamin K intake and the risk of fractures: A meta-analysisMedicine (Baltimore).(2017 Apr)
VITAMINA B1210 riferimenti
- Depeint F, Bruce WR, Shangari N, Mehta R, O'Brien PJMitochondrial function and toxicity: role of the B vitamin family on mitochondrial energy metabolismChem Biol Interact.(2006 Oct 27)
- Selhub JFolate, vitamin B12 and vitamin B6 and one carbon metabolismJ Nutr Health Aging.(2002)
- Chen AC, Martin AJ, Choy B, Fernández-Peñas P, Dalziell RA, McKenzie CA, Scolyer RA, Dhillon HM, Vardy JL, Kricker A, St George G, Chinniah N, Halliday GM, Damian DLA Phase 3 Randomized Trial of Nicotinamide for Skin-Cancer ChemopreventionN Engl J Med.(2015 Oct 22)
- Brasky TM, White E, Chen CLLong-Term, Supplemental, One-Carbon Metabolism-Related Vitamin B Use in Relation to Lung Cancer Risk in the Vitamins and Lifestyle (VITAL) CohortJ Clin Oncol.(2017 Oct 20)
- White E, Patterson RE, Kristal AR, Thornquist M, King I, Shattuck AL, Evans I, Satia-Abouta J, Littman AJ, Potter JDVITamins And Lifestyle cohort study: study design and characteristics of supplement usersAm J Epidemiol.(2004 Jan 1)
- Kim YIFolate and colorectal cancer: an evidence-based critical reviewMol Nutr Food Res.(2007 Mar)
- Kok DE, Dhonukshe-Rutten RA, Lute C, Heil SG, Uitterlinden AG, van der Velde N, van Meurs JB, van Schoor NM, Hooiveld GJ, de Groot LC, Kampman E, Steegenga WTThe effects of long-term daily folic acid and vitamin B12 supplementation on genome-wide DNA methylation in elderly subjectsClin Epigenetics.(2015 Nov 14)
- Corbin JM, Ruiz-Echevarría MJOne-Carbon Metabolism in Prostate Cancer: The Role of Androgen SignalingInt J Mol Sci.(2016 Jul 27)
- Fatigue Symptoms - Huijts M, van Oostenbrugge RJ, Rouhl RP, Menheere P, Duits AEffects of vitamin B12 supplementation on cognition, depression, and fatigue in patients with lacunar strokeInt Psychogeriatr.(2013 Mar)
- Homocysteine - Hill MH, Flatley JE, Barker ME, Garner CM, Manning NJ, Olpin SE, Moat SJ, Russell J, Powers HJA vitamin B-12 supplement of 500 μg/d for eight weeks does not normalize urinary methylmalonic acid or other biomarkers of vitamin B-12 status in elderly people with moderately poor vitamin B-12 statusJ Nutr.(2013 Feb)
VITAMINA B611 riferimenti
- Depeint F, Bruce WR, Shangari N, Mehta R, O'Brien PJMitochondrial function and toxicity: role of the B vitamin family on mitochondrial energy metabolismChem Biol Interact.(2006 Oct 27)
- Selhub JFolate, vitamin B12 and vitamin B6 and one carbon metabolismJ Nutr Health Aging.(2002)
- Chen AC, Martin AJ, Choy B, Fernández-Peñas P, Dalziell RA, McKenzie CA, Scolyer RA, Dhillon HM, Vardy JL, Kricker A, St George G, Chinniah N, Halliday GM, Damian DLA Phase 3 Randomized Trial of Nicotinamide for Skin-Cancer ChemopreventionN Engl J Med.(2015 Oct 22)
- Brasky TM, White E, Chen CLLong-Term, Supplemental, One-Carbon Metabolism-Related Vitamin B Use in Relation to Lung Cancer Risk in the Vitamins and Lifestyle (VITAL) CohortJ Clin Oncol.(2017 Oct 20)
- White E, Patterson RE, Kristal AR, Thornquist M, King I, Shattuck AL, Evans I, Satia-Abouta J, Littman AJ, Potter JDVITamins And Lifestyle cohort study: study design and characteristics of supplement usersAm J Epidemiol.(2004 Jan 1)
- Kim YIFolate and colorectal cancer: an evidence-based critical reviewMol Nutr Food Res.(2007 Mar)
- Kok DE, Dhonukshe-Rutten RA, Lute C, Heil SG, Uitterlinden AG, van der Velde N, van Meurs JB, van Schoor NM, Hooiveld GJ, de Groot LC, Kampman E, Steegenga WTThe effects of long-term daily folic acid and vitamin B12 supplementation on genome-wide DNA methylation in elderly subjectsClin Epigenetics.(2015 Nov 14)
- Corbin JM, Ruiz-Echevarría MJOne-Carbon Metabolism in Prostate Cancer: The Role of Androgen SignalingInt J Mol Sci.(2016 Jul 27)
- High-density lipoprotein (HDL) - Alaei-Shahmiri F, Soares MJ, Zhao Y, Sherriff JThe impact of thiamine supplementation on blood pressure, serum lipids and C-reactive protein in individuals with hyperglycemia: a randomised, double-blind cross-over trialDiabetes Metab Syndr.(2015 Oct-Dec)
- PMS Symptoms - Abdollahifard S, Rahmanian Koshkaki A, Moazamiyanfar RThe effects of vitamin B1 on ameliorating the premenstrual syndrome symptomsGlob J Health Sci.(2014 Jul 29)
- PMS Symptoms - Samieipour S, et al.EFFECT OF CALCIUM AND VITAMIN B1 ON THE SEVERITY OF PREMENSTRUAL SYNDROME: A RANDOMIZED CONTROL TRIALInt J Pharm Tech.()
ACIDO FOLICO10 riferimenti
- Depeint F, Bruce WR, Shangari N, Mehta R, O'Brien PJMitochondrial function and toxicity: role of the B vitamin family on mitochondrial energy metabolismChem Biol Interact.(2006 Oct 27)
- Selhub JFolate, vitamin B12 and vitamin B6 and one carbon metabolismJ Nutr Health Aging.(2002)
- Chen AC, Martin AJ, Choy B, Fernández-Peñas P, Dalziell RA, McKenzie CA, Scolyer RA, Dhillon HM, Vardy JL, Kricker A, St George G, Chinniah N, Halliday GM, Damian DLA Phase 3 Randomized Trial of Nicotinamide for Skin-Cancer ChemopreventionN Engl J Med.(2015 Oct 22)
- Brasky TM, White E, Chen CLLong-Term, Supplemental, One-Carbon Metabolism-Related Vitamin B Use in Relation to Lung Cancer Risk in the Vitamins and Lifestyle (VITAL) CohortJ Clin Oncol.(2017 Oct 20)
- White E, Patterson RE, Kristal AR, Thornquist M, King I, Shattuck AL, Evans I, Satia-Abouta J, Littman AJ, Potter JDVITamins And Lifestyle cohort study: study design and characteristics of supplement usersAm J Epidemiol.(2004 Jan 1)
- Kim YIFolate and colorectal cancer: an evidence-based critical reviewMol Nutr Food Res.(2007 Mar)
- Kok DE, Dhonukshe-Rutten RA, Lute C, Heil SG, Uitterlinden AG, van der Velde N, van Meurs JB, van Schoor NM, Hooiveld GJ, de Groot LC, Kampman E, Steegenga WTThe effects of long-term daily folic acid and vitamin B12 supplementation on genome-wide DNA methylation in elderly subjectsClin Epigenetics.(2015 Nov 14)
- Corbin JM, Ruiz-Echevarría MJOne-Carbon Metabolism in Prostate Cancer: The Role of Androgen SignalingInt J Mol Sci.(2016 Jul 27)
- Depression Symptoms - Taylor MJ, Carney S, Geddes J, Goodwin GFolate for depressive disordersCochrane Database Syst Rev.(2003)
- Depression Symptoms - Godfrey PS, Toone BK, Carney MW, Flynn TG, Bottiglieri T, Laundy M, Chanarin I, Reynolds EHEnhancement of recovery from psychiatric illness by methylfolateLancet.(1990 Aug 18)
VITAMINA B111 riferimenti
- Depeint F, Bruce WR, Shangari N, Mehta R, O'Brien PJMitochondrial function and toxicity: role of the B vitamin family on mitochondrial energy metabolismChem Biol Interact.(2006 Oct 27)
- Selhub JFolate, vitamin B12 and vitamin B6 and one carbon metabolismJ Nutr Health Aging.(2002)
- Chen AC, Martin AJ, Choy B, Fernández-Peñas P, Dalziell RA, McKenzie CA, Scolyer RA, Dhillon HM, Vardy JL, Kricker A, St George G, Chinniah N, Halliday GM, Damian DLA Phase 3 Randomized Trial of Nicotinamide for Skin-Cancer ChemopreventionN Engl J Med.(2015 Oct 22)
- Brasky TM, White E, Chen CLLong-Term, Supplemental, One-Carbon Metabolism-Related Vitamin B Use in Relation to Lung Cancer Risk in the Vitamins and Lifestyle (VITAL) CohortJ Clin Oncol.(2017 Oct 20)
- White E, Patterson RE, Kristal AR, Thornquist M, King I, Shattuck AL, Evans I, Satia-Abouta J, Littman AJ, Potter JDVITamins And Lifestyle cohort study: study design and characteristics of supplement usersAm J Epidemiol.(2004 Jan 1)
- Kim YIFolate and colorectal cancer: an evidence-based critical reviewMol Nutr Food Res.(2007 Mar)
- Kok DE, Dhonukshe-Rutten RA, Lute C, Heil SG, Uitterlinden AG, van der Velde N, van Meurs JB, van Schoor NM, Hooiveld GJ, de Groot LC, Kampman E, Steegenga WTThe effects of long-term daily folic acid and vitamin B12 supplementation on genome-wide DNA methylation in elderly subjectsClin Epigenetics.(2015 Nov 14)
- Corbin JM, Ruiz-Echevarría MJOne-Carbon Metabolism in Prostate Cancer: The Role of Androgen SignalingInt J Mol Sci.(2016 Jul 27)
- High-density lipoprotein (HDL) - Alaei-Shahmiri F, Soares MJ, Zhao Y, Sherriff JThe impact of thiamine supplementation on blood pressure, serum lipids and C-reactive protein in individuals with hyperglycemia: a randomised, double-blind cross-over trialDiabetes Metab Syndr.(2015 Oct-Dec)
- PMS Symptoms - Abdollahifard S, Rahmanian Koshkaki A, Moazamiyanfar RThe effects of vitamin B1 on ameliorating the premenstrual syndrome symptomsGlob J Health Sci.(2014 Jul 29)
- PMS Symptoms - Samieipour S, et al.EFFECT OF CALCIUM AND VITAMIN B1 ON THE SEVERITY OF PREMENSTRUAL SYNDROME: A RANDOMIZED CONTROL TRIALInt J Pharm Tech.()
VITAMINA B222 riferimenti
- Depeint F, Bruce WR, Shangari N, Mehta R, O'Brien PJMitochondrial function and toxicity: role of the B vitamin family on mitochondrial energy metabolismChem Biol Interact.(2006 Oct 27)
- Selhub JFolate, vitamin B12 and vitamin B6 and one carbon metabolismJ Nutr Health Aging.(2002)
- Chen AC, Martin AJ, Choy B, Fernández-Peñas P, Dalziell RA, McKenzie CA, Scolyer RA, Dhillon HM, Vardy JL, Kricker A, St George G, Chinniah N, Halliday GM, Damian DLA Phase 3 Randomized Trial of Nicotinamide for Skin-Cancer ChemopreventionN Engl J Med.(2015 Oct 22)
- Brasky TM, White E, Chen CLLong-Term, Supplemental, One-Carbon Metabolism-Related Vitamin B Use in Relation to Lung Cancer Risk in the Vitamins and Lifestyle (VITAL) CohortJ Clin Oncol.(2017 Oct 20)
- White E, Patterson RE, Kristal AR, Thornquist M, King I, Shattuck AL, Evans I, Satia-Abouta J, Littman AJ, Potter JDVITamins And Lifestyle cohort study: study design and characteristics of supplement usersAm J Epidemiol.(2004 Jan 1)
- Kim YIFolate and colorectal cancer: an evidence-based critical reviewMol Nutr Food Res.(2007 Mar)
- Kok DE, Dhonukshe-Rutten RA, Lute C, Heil SG, Uitterlinden AG, van der Velde N, van Meurs JB, van Schoor NM, Hooiveld GJ, de Groot LC, Kampman E, Steegenga WTThe effects of long-term daily folic acid and vitamin B12 supplementation on genome-wide DNA methylation in elderly subjectsClin Epigenetics.(2015 Nov 14)
- Corbin JM, Ruiz-Echevarría MJOne-Carbon Metabolism in Prostate Cancer: The Role of Androgen SignalingInt J Mol Sci.(2016 Jul 27)
- Homocysteine - McKinley MC, McNulty H, McPartlin J, Strain JJ, Scott JMEffect of riboflavin supplementation on plasma homocysteine in elderly people with low riboflavin statusEur J Clin Nutr.(2002 Sep)
- Homocysteine - Tavares NR, Moreira PA, Amaral TFRiboflavin supplementation and biomarkers of cardiovascular disease in the elderlyJ Nutr Health Aging.(2009 May)
- Homocysteine - Naghashpour M, Majdinasab N, Shakerinejad G, Kouchak M, Haghighizadeh MH, Jarvandi F, Hajinajaf SRiboflavin supplementation to patients with multiple sclerosis does not improve disability status nor is riboflavin supplementation correlated to homocysteineInt J Vitam Nutr Res.(2013)
- Homocysteine - McNulty H, Dowey le RC, Strain JJ, Dunne A, Ward M, Molloy AM, McAnena LB, Hughes JP, Hannon-Fletcher M, Scott JMRiboflavin lowers homocysteine in individuals homozygous for the MTHFR 677C->T polymorphismCirculation.(2006 Jan 3)
- Blood Pressure - Wilson CP, Ward M, McNulty H, Strain JJ, Trouton TG, Horigan G, Purvis J, Scott JMRiboflavin offers a targeted strategy for managing hypertension in patients with the MTHFR 677TT genotype: a 4-y follow-upAm J Clin Nutr.(2012 Mar)
- Blood Pressure - Horigan G, McNulty H, Ward M, Strain JJ, Purvis J, Scott JMRiboflavin lowers blood pressure in cardiovascular disease patients homozygous for the 677C-->T polymorphism in MTHFRJ Hypertens.(2010 Mar)
- Blood Pressure - Wilson CP, McNulty H, Ward M, Strain JJ, Trouton TG, Hoeft BA, Weber P, Roos FF, Horigan G, McAnena L, Scott JMBlood pressure in treated hypertensive individuals with the MTHFR 677TT genotype is responsive to intervention with riboflavin: findings of a targeted randomized trialHypertension.(2013 Jun)
- Migraine Symptoms - Condò M, Posar A, Arbizzani A, Parmeggiani ARiboflavin prophylaxis in pediatric and adolescent migraineJ Headache Pain.(2009 Oct)
- Migraine Symptoms - C Di Lorenzo, F Pierelli, G Coppola, G S Grieco, C Rengo, M Ciccolella, D Magis, M Bolla, C Casali, F M Santorelli, J SchoenenMitochondrial DNA haplogroups influence the therapeutic response to riboflavin in migraineursNeurology.(2009 May 5)
- Migraine Symptoms - Bruijn J, Duivenvoorden H, Passchier J, Locher H, Dijkstra N, Arts WFMedium-dose riboflavin as a prophylactic agent in children with migraine: a preliminary placebo-controlled, randomised, double-blind, cross-over trialCephalalgia.(2010 Dec)
- Migraine Symptoms - Boehnke C, Reuter U, Flach U, Schuh-Hofer S, Einhäupl KM, Arnold GHigh-dose riboflavin treatment is efficacious in migraine prophylaxis: an open study in a tertiary care centreEur J Neurol.(2004 Jul)
- Migraine Symptoms - Schoenen J, Jacquy J, Lenaerts MEffectiveness of high-dose riboflavin in migraine prophylaxis. A randomized controlled trialNeurology.(1998 Feb)
- Migraine Symptoms - Maizels M, Blumenfeld A, Burchette RA combination of riboflavin, magnesium, and feverfew for migraine prophylaxis: a randomized trialHeadache.(2004 Oct)
- Migraine Symptoms - MacLennan SC, Wade FM, Forrest KM, Ratanayake PD, Fagan E, Antony JHigh-dose riboflavin for migraine prophylaxis in children: a double-blind, randomized, placebo-controlled trialJ Child Neurol.(2008 Nov)
VITAMINA B325 riferimenti
- Depeint F, Bruce WR, Shangari N, Mehta R, O'Brien PJMitochondrial function and toxicity: role of the B vitamin family on mitochondrial energy metabolismChem Biol Interact.(2006 Oct 27)
- Selhub JFolate, vitamin B12 and vitamin B6 and one carbon metabolismJ Nutr Health Aging.(2002)
- Chen AC, Martin AJ, Choy B, Fernández-Peñas P, Dalziell RA, McKenzie CA, Scolyer RA, Dhillon HM, Vardy JL, Kricker A, St George G, Chinniah N, Halliday GM, Damian DLA Phase 3 Randomized Trial of Nicotinamide for Skin-Cancer ChemopreventionN Engl J Med.(2015 Oct 22)
- Brasky TM, White E, Chen CLLong-Term, Supplemental, One-Carbon Metabolism-Related Vitamin B Use in Relation to Lung Cancer Risk in the Vitamins and Lifestyle (VITAL) CohortJ Clin Oncol.(2017 Oct 20)
- White E, Patterson RE, Kristal AR, Thornquist M, King I, Shattuck AL, Evans I, Satia-Abouta J, Littman AJ, Potter JDVITamins And Lifestyle cohort study: study design and characteristics of supplement usersAm J Epidemiol.(2004 Jan 1)
- Kim YIFolate and colorectal cancer: an evidence-based critical reviewMol Nutr Food Res.(2007 Mar)
- Kok DE, Dhonukshe-Rutten RA, Lute C, Heil SG, Uitterlinden AG, van der Velde N, van Meurs JB, van Schoor NM, Hooiveld GJ, de Groot LC, Kampman E, Steegenga WTThe effects of long-term daily folic acid and vitamin B12 supplementation on genome-wide DNA methylation in elderly subjectsClin Epigenetics.(2015 Nov 14)
- Corbin JM, Ruiz-Echevarría MJOne-Carbon Metabolism in Prostate Cancer: The Role of Androgen SignalingInt J Mol Sci.(2016 Jul 27)
- Low-density lipoprotein (LDL) - Westphal S, Borucki K, Taneva E, Makarova R, Luley CExtended-release niacin raises adiponectin and leptinAtherosclerosis.(2007 Aug)
- Low-density lipoprotein (LDL) - Kelly JJ, Lawson JA, Campbell LV, Storlien LH, Jenkins AB, Whitworth JA, O'Sullivan AJEffects of nicotinic acid on insulin sensitivity and blood pressure in healthy subjectsJ Hum Hypertens.(2000 Sep)
- Ketone Bodies - Chen X, Iqbal N, Boden GThe effects of free fatty acids on gluconeogenesis and glycogenolysis in normal subjectsJ Clin Invest.(1999 Feb)
- Insulin - Chang AM, Smith MJ, Galecki AT, Bloem CJ, Halter JBImpaired beta-cell function in human aging: response to nicotinic acid-induced insulin resistanceJ Clin Endocrinol Metab.(2006 Sep)
- Insulin - Fraterrigo G, Fabbrini E, Mittendorfer B, O'Rahilly S, Scherer PE, Patterson BW, Klein SRelationship between Changes in Plasma Adiponectin Concentration and Insulin Sensitivity after Niacin TherapyCardiorenal Med.(2012 Aug)
- Wound Healing - Gebicki J, Sysa-Jedrzejowska A, Adamus J, Woźniacka A, Rybak M, Zielonka J1-Methylnicotinamide: a potent anti-inflammatory agent of vitamin originPol J Pharmacol.(2003 Jan-Feb)
- Blood glucose - Valeria Nasser Figueiredo, Felipe Vendrame, Bruno A Colontoni, Thiago Quinaglia, Jose Roberto Matos-Souza, Filipe Azevedo Moura, Otavio R Coelho, Eliana C de Faria, Andrei C SpositoShort-term effects of extended-release niacin with and without the addition of laropiprant on endothelial function in individuals with low HDL-C: a randomized, controlled crossover trialClin Ther.(2014 Jun 1)
- Apolipoprotein B - T Sakai, V S Kamanna, M L KashyapNiacin, but not gemfibrozil, selectively increases LP-AI, a cardioprotective subfraction of HDL, in patients with low HDL cholesterolArterioscler Thromb Vasc Biol.(2001 Nov)
- Total cholesterol - No authors listedClofibrate and niacin in coronary heart diseaseJAMA.(1975 Jan 27)
- Stroke Risk - Jasleen K. Duggal, Mukesh Singh, Navneet Attri, Param P. Singh, Neyaz Ahmed, Suneet Pahwa, Janos Molnar, Sarabjeet Singh, Sandeep Khosla, Rohit AroraEffect of Niacin Therapy on Cardiovascular Outcomes in Patients With Coronary Artery DiseaseJournal of Cardiovascular Pharmacology and Therapeutics.()
- High-density lipoprotein (HDL) - Blond E, Rieusset J, Alligier M, Lambert-Porcheron S, Bendridi N, Gabert L, Chetiveaux M, Debard C, Chauvin MA, Normand S, Roth H, de Gouville AC, Krempf M, Vidal H, Goudable J, Laville M, “Niacin” Study GroupNicotinic acid effects on insulin sensitivity and hepatic lipid metabolism: an in vivo to in vitro studyHorm Metab Res.(2014 Jun)
- Apolipoprotein A - AIM-HIGH Investigators, Boden WE, Probstfield JL, Anderson T, Chaitman BR, Desvignes-Nickens P, Koprowicz K, McBride R, Teo K, Weintraub WNiacin in patients with low HDL cholesterol levels receiving intensive statin therapyN Engl J Med.(2011 Dec 15)
- Apolipoprotein B - Fabbrini E, Mohammed BS, Korenblat KM, Magkos F, McCrea J, Patterson BW, Klein SEffect of fenofibrate and niacin on intrahepatic triglyceride content, very low-density lipoprotein kinetics, and insulin action in obese subjects with nonalcoholic fatty liver diseaseJ Clin Endocrinol Metab.(2010 Jun)
- Erythema - Bissett DL, Oblong JE, Berge CANiacinamide: A B vitamin that improves aging facial skin appearanceDermatol Surg.(2005 Jul)
- Skin Quality - Hakozaki T, Minwalla L, Zhuang J, Chhoa M, Matsubara A, Miyamoto K, Greatens A, Hillebrand GG, Bissett DL, Boissy REThe effect of niacinamide on reducing cutaneous pigmentation and suppression of melanosome transferBr J Dermatol.(2002 Jul)
- Acne Symptoms - Khodaeiani E, Fouladi RF, Amirnia M, Saeidi M, Karimi ERTopical 4% nicotinamide vs. 1% clindamycin in moderate inflammatory acne vulgarisInt J Dermatol.(2013 Aug)
- Acne Symptoms - Shalita AR, Smith JG, Parish LC, Sofman MS, Chalker DKTopical nicotinamide compared with clindamycin gel in the treatment of inflammatory acne vulgarisInt J Dermatol.(1995 Jun)
VITAMINA B58 riferimenti
- Depeint F, Bruce WR, Shangari N, Mehta R, O'Brien PJMitochondrial function and toxicity: role of the B vitamin family on mitochondrial energy metabolismChem Biol Interact.(2006 Oct 27)
- Selhub JFolate, vitamin B12 and vitamin B6 and one carbon metabolismJ Nutr Health Aging.(2002)
- Chen AC, Martin AJ, Choy B, Fernández-Peñas P, Dalziell RA, McKenzie CA, Scolyer RA, Dhillon HM, Vardy JL, Kricker A, St George G, Chinniah N, Halliday GM, Damian DLA Phase 3 Randomized Trial of Nicotinamide for Skin-Cancer ChemopreventionN Engl J Med.(2015 Oct 22)
- Brasky TM, White E, Chen CLLong-Term, Supplemental, One-Carbon Metabolism-Related Vitamin B Use in Relation to Lung Cancer Risk in the Vitamins and Lifestyle (VITAL) CohortJ Clin Oncol.(2017 Oct 20)
- White E, Patterson RE, Kristal AR, Thornquist M, King I, Shattuck AL, Evans I, Satia-Abouta J, Littman AJ, Potter JDVITamins And Lifestyle cohort study: study design and characteristics of supplement usersAm J Epidemiol.(2004 Jan 1)
- Kim YIFolate and colorectal cancer: an evidence-based critical reviewMol Nutr Food Res.(2007 Mar)
- Kok DE, Dhonukshe-Rutten RA, Lute C, Heil SG, Uitterlinden AG, van der Velde N, van Meurs JB, van Schoor NM, Hooiveld GJ, de Groot LC, Kampman E, Steegenga WTThe effects of long-term daily folic acid and vitamin B12 supplementation on genome-wide DNA methylation in elderly subjectsClin Epigenetics.(2015 Nov 14)
- Corbin JM, Ruiz-Echevarría MJOne-Carbon Metabolism in Prostate Cancer: The Role of Androgen SignalingInt J Mol Sci.(2016 Jul 27)
BIOTINA25 riferimenti
- Institute of Medicine Food and Nutrition Board. Dietary Reference Intakes: Thiamin, Riboflavin, Niacin, Vitamin B6, Folate, Vitamin B12, Pantothenic Acid, Biotin, and Choline.National Academy Press.(1998)
- Bistas KG, Tadi P.Biotin StatPearls.(2023)
- Barbesino GMisdiagnosis of Graves' Disease with Apparent Severe Hyperthyroidism in a Patient Taking Biotin Megadoses.Thyroid.(2016-Jun)
- Piketty ML, Polak M, Flechtner I, Gonzales-Briceño L, Souberbielle JCFalse biochemical diagnosis of hyperthyroidism in streptavidin-biotin-based immunoassays: the problem of biotin intake and related interferences.Clin Chem Lab Med.(2017-May-01)
- Li D, Radulescu A, Shrestha RT, Root M, Karger AB, Killeen AA, Hodges JS, Fan SL, Ferguson A, Garg U, Sokoll LJ, Burmeister LAAssociation of Biotin Ingestion With Performance of Hormone and Nonhormone Assays in Healthy Adults.JAMA.(2017-Sep-26)
- Ali M, Rajapakshe D, Cao L, Devaraj SDiscordant Analytical Results Caused by Biotin Interference on Diagnostic Immunoassays in a Pediatric Hospital.Ann Clin Lab Sci.(2017-Sep)
- Goodrum JM, Nair VS, Moore C, Crouch AK, Eichner D, Miller GDImpact of Biotin Supplementation on Human Chorionic Gonadotropin Immunoassays Utilizing Biotin-Streptavidin Binding Methods in Urine.Clin Chem.(2023-Jul-05)
- James A, Stalan J, Kuzhively JBiotin induced biochemical hyperthyroidism: a case report and review of the literature.J Med Case Rep.(2023-Jun-28)
- Elston MS, Sehgal S, Du Toit S, Yarndley T, Conaglen JVFactitious Graves' Disease Due to Biotin Immunoassay Interference-A Case and Review of the Literature.J Clin Endocrinol Metab.(2016-Sep)
- Harley K, Bissonnette S, Inzitari R, Schulz K, Apple FS, Kavsak PA, Gunsolus ILIndependent and combined effects of biotin and hemolysis on high-sensitivity cardiac troponin assays.Clin Chem Lab Med.(2021-Jul-27)
- Depeint F, Bruce WR, Shangari N, Mehta R, O'Brien PJMitochondrial function and toxicity: role of the B vitamin family on mitochondrial energy metabolismChem Biol Interact.(2006 Oct 27)
- Selhub JFolate, vitamin B12 and vitamin B6 and one carbon metabolismJ Nutr Health Aging.(2002)
- Chen AC, Martin AJ, Choy B, Fernández-Peñas P, Dalziell RA, McKenzie CA, Scolyer RA, Dhillon HM, Vardy JL, Kricker A, St George G, Chinniah N, Halliday GM, Damian DLA Phase 3 Randomized Trial of Nicotinamide for Skin-Cancer ChemopreventionN Engl J Med.(2015 Oct 22)
- Brasky TM, White E, Chen CLLong-Term, Supplemental, One-Carbon Metabolism-Related Vitamin B Use in Relation to Lung Cancer Risk in the Vitamins and Lifestyle (VITAL) CohortJ Clin Oncol.(2017 Oct 20)
- White E, Patterson RE, Kristal AR, Thornquist M, King I, Shattuck AL, Evans I, Satia-Abouta J, Littman AJ, Potter JDVITamins And Lifestyle cohort study: study design and characteristics of supplement usersAm J Epidemiol.(2004 Jan 1)
- Kim YIFolate and colorectal cancer: an evidence-based critical reviewMol Nutr Food Res.(2007 Mar)
- Kok DE, Dhonukshe-Rutten RA, Lute C, Heil SG, Uitterlinden AG, van der Velde N, van Meurs JB, van Schoor NM, Hooiveld GJ, de Groot LC, Kampman E, Steegenga WTThe effects of long-term daily folic acid and vitamin B12 supplementation on genome-wide DNA methylation in elderly subjectsClin Epigenetics.(2015 Nov 14)
- Corbin JM, Ruiz-Echevarría MJOne-Carbon Metabolism in Prostate Cancer: The Role of Androgen SignalingInt J Mol Sci.(2016 Jul 27)
- Blood glucose - Revilla-Monsalve C, Zendejas-Ruiz I, Islas-Andrade S, Báez-Saldaña A, Palomino-Garibay MA, Hernández-Quiróz PM, Fernandez-Mejia CBiotin supplementation reduces plasma triacylglycerol and VLDL in type 2 diabetic patients and in nondiabetic subjects with hypertriglyceridemiaBiomed Pharmacother.(2006 May)
- Multiple Sclerosis Symptoms - Bruce A C Cree, Gary Cutter, Jerry S Wolinsky, Mark S Freedman, Giancarlo Comi, Gavin Giovannoni, Hans-Peter Hartung, Douglas Arnold, Jens Kuhle, Valerie Block, Frederick E Munschauer, Frédéric Sedel, Fred D Lublin, SPI2 investigative teamsSafety and efficacy of MD1003 (high-dose biotin) in patients with progressive multiple sclerosis (SPI2): a randomised, double-blind, placebo-controlled, phase 3 trialLancet Neurol.(2020 Dec)
- Multiple Sclerosis Symptoms - Tourbah A, Lebrun-Frenay C, Edan G, Clanet M, Papeix C, Vukusic S, De Sèze J, Debouverie M, Gout O, Clavelou P, Defer G, Laplaud DA, Moreau T, Labauge P, Brochet B, Sedel F, Pelletier J, MD1003 (high-dose biotin) for the treatment of progressive multiple sclerosis: A randomised, double-blind, placebo-controlled study.Mult Scler.(2016-11)
- Multiple Sclerosis Symptoms - Sedel F, Papeix C, Bellanger A, Touitou V, Lebrun-Frenay C, Galanaud D, Gout O, Lyon-Caen O, Tourbah AHigh doses of biotin in chronic progressive multiple sclerosis: a pilot study.Mult Scler Relat Disord.(2015-Mar)
- Multiple Sclerosis Symptoms - Tourbah A, Gout O, Vighetto A, Deburghgraeve V, Pelletier J, Papeix C, Lebrun-Frenay C, Labauge P, Brassat D, Toosy A, Laplaud DA, Outteryck O, Moreau T, Debouverie M, Clavelou P, Heinzlef O, De Sèze J, Defer G, Sedel F, Arndt CMD1003 (High-Dose Pharmaceutical-Grade Biotin) for the Treatment of Chronic Visual Loss Related to Optic Neuritis in Multiple Sclerosis: A Randomized, Double-Blind, Placebo-Controlled Study.CNS Drugs.(2018-07)
- Triglycerides - Marshall MW, Kliman PG, Washington VA, Mackin JF, Weinland BTEffects of biotin on lipids and other constituents of plasma of healthy men and womenArtery.(1980)
- Nail Quality - Colombo VE, Gerber F, Bronhofer M, Floersheim GLTreatment of brittle fingernails and onychoschizia with biotin: scanning electron microscopyJ Am Acad Dermatol.(1990 Dec)