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Exercise-Induced Oxidation - Nakhostin-Roohi B, Babaei P, Rahmani-Nia F, Bohlooli SEffect of vitamin C supplementation on lipid peroxidation, muscle damage and inflammation after 30-min exercise at 75% VO2maxJ Sports Med Phys Fitness.(2008 Jun)

Exercise-Induced Oxidation - Bryant RJ, Ryder J, Martino P, Kim J, Craig BWEffects of vitamin E and C supplementation either alone or in combination on exercise-induced lipid peroxidation in trained cyclistsJ Strength Cond Res.(2003 Nov)

Cortisol - Davison G, Gleeson MThe effect of 2 weeks vitamin C supplementation on immunoendocrine responses to 2.5 h cycling exercise in manEur J Appl Physiol.(2006 Jul)

Cortisol - Glen Davison, Michael GleesonInfluence of acute vitamin C and/or carbohydrate ingestion on hormonal, cytokine, and immune responses to prolonged exerciseInt J Sport Nutr Exerc Metab.(2005 Oct)

Resistin - Bo S, Ciccone G, Durazzo M, Gambino R, Massarenti P, Baldi I, Lezo A, Tiozzo E, Pauletto D, Cassader M, Pagano GEfficacy of antioxidant treatment in reducing resistin serum levels: a randomized studyPLoS Clin Trials.(2007 May 4)

Inflammation - Colby JA, Chen WT, Baker WL, Coleman CI, Reinhart K, Kluger J, White CMEffect of ascorbic acid on inflammatory markers after cardiothoracic surgeryAm J Health Syst Pharm.(2011 Sep 1)

Blood Flow - Sergio De Marchi, Manlio Prior, Anna Rigoni, Sara Zecchetto, Fanny Rulfo, Enrico ArosioAscorbic acid prevents vascular dysfunction induced by oral glucose load in healthy subjectsEur J Intern Med.(2012 Jan)

General Oxidation - Kuiper HC, Bruno RS, Traber MG, Stevens JFVitamin C supplementation lowers urinary levels of 4-hydroperoxy-2-nonenal metabolites in humansFree Radic Biol Med.(2011 Apr 1)

General Oxidation - Retana-Ugalde R, Casanueva E, Altamirano-Lozano M, González-Torres C, Mendoza-Núñez VMHigh dosage of ascorbic acid and alpha-tocopherol is not useful for diminishing oxidative stress and DNA damage in healthy elderly adultsAnn Nutr Metab.(2008)

Lipid Peroxidation - Johnston CS, Dancho CL, Strong GMOrange juice ingestion and supplemental vitamin C are equally effective at reducing plasma lipid peroxidation in healthy adult womenJ Am Coll Nutr.(2003 Dec)

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Blood glucose - Johnston CS, Yen MFMegadose of vitamin C delays insulin response to a glucose challenge in normoglycemic adultsAm J Clin Nutr.(1994 Nov)

Protection from Smoking - Fuller CJ, May MA, Martin KJThe effect of vitamin E and vitamin C supplementation on LDL oxidizability and neutrophil respiratory burst in young smokersJ Am Coll Nutr.(2000 Jun)

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DNA Damage - Guarnieri S, Riso P, Porrini MOrange juice vs vitamin C: effect on hydrogen peroxide-induced DNA damage in mononuclear blood cellsBr J Nutr.(2007 Apr)

Mineral Bioaccumulation - Calabrese EJ, Stoddard A, Leonard DA, Dinardi SRThe effects of vitamin C supplementation on blood and hair levels of cadmium, lead, and mercuryAnn N Y Acad Sci.(1987)

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Upper Respiratory Tract Infection Symptoms - Anderson TW, Reid DB, Beaton GHVitamin C and the common cold: a double-blind trialCan Med Assoc J.(1972 Sep 23)

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Upper Respiratory Tract Infection Risk - Kim TK, Lim HR, Byun JSVitamin C supplementation reduces the odds of developing a common cold in Republic of Korea Army recruits: randomised controlled trialBMJ Mil Health.(2020 Mar 5)

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Total cholesterol - Knab AM, Shanely RA, Henson DA, Jin F, Heinz SA, Austin MD, Nieman DCInfluence of quercetin supplementation on disease risk factors in community-dwelling adultsJ Am Diet Assoc.(2011 Apr)

Interferon Gamma - Nieman DC, Henson DA, McAnulty SR, McAnulty L, Swick NS, Utter AC, Vinci DM, Opiela SJ, Morrow JDInfluence of vitamin C supplementation on oxidative and immune changes after an ultramarathonJ Appl Physiol (1985).(2002 May)

Cortisol - Carrillo AE, Murphy RJ, Cheung SSVitamin C supplementation and salivary immune function following exercise-heat stressInt J Sports Physiol Perform.(2008 Dec)

Cortisol - Palmer FM, Nieman DC, Henson DA, McAnulty SR, McAnulty L, Swick NS, Utter AC, Vinci DM, Morrow JDInfluence of vitamin C supplementation on oxidative and salivary IgA changes following an ultramarathonEur J Appl Physiol.(2003 Mar)

Upper Respiratory Tract Infection Risk - Baird IM, Hughes RE, Wilson HK, Davies JE, Howard ANThe effects of ascorbic acid and flavonoids on the occurrence of symptoms normally associated with the common coldAm J Clin Nutr.(1979 Aug)

Inflammation - Thompson D, Bailey DM, Hill J, Hurst T, Powell JR, Williams CProlonged vitamin C supplementation and recovery from eccentric exerciseEur J Appl Physiol.(2004 Jun)

Muscle Damage - Bryer SC, Goldfarb AHEffect of high dose vitamin C supplementation on muscle soreness, damage, function, and oxidative stress to eccentric exerciseInt J Sport Nutr Exerc Metab.(2006 Jun)

Muscle Damage - Theodorou AA, Nikolaidis MG, Paschalis V, Koutsias S, Panayiotou G, Fatouros IG, Koutedakis Y, Jamurtas AZNo effect of antioxidant supplementation on muscle performance and blood redox status adaptations to eccentric trainingAm J Clin Nutr.(2011 Jun)

Aerobic Exercise Metrics - Roberts LA, Beattie K, Close GL, Morton JPVitamin C consumption does not impair training-induced improvements in exercise performanceInt J Sports Physiol Perform.(2011 Mar)

Aerobic Exercise Metrics - Ataka S, Tanaka M, Nozaki S, Mizuma H, Mizuno K, Tahara T, Sugino T, Shirai T, Kajimoto Y, Kuratsune H, Kajimoto O, Watanabe YEffects of Applephenon and ascorbic acid on physical fatigueNutrition.(2007 May)

Cortisol - Pirbudak L, Balat O, Cekmen M, Ugur MG, Aygün S, Oner UEffect of ascorbic acid on surgical stress response in gynecologic surgeryInt J Clin Pract.(2004 Oct)

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Plasma Vitamin C - Davison GW, Ashton T, George L, Young IS, McEneny J, Davies B, Jackson SK, Peters JR, Bailey DMMolecular detection of exercise-induced free radicals following ascorbate prophylaxis in type 1 diabetes mellitus: a randomised controlled trialDiabetologia.(2008 Nov)

General Oxidation - Van Hoydonck PG, Schouten EG, Manuel-Y-Keenoy B, van Campenhout A, Hoppenbrouwers KP, Temme EHDoes vitamin C supplementation influence the levels of circulating oxidized LDL, sICAM-1, sVCAM-1 and vWF-antigen in healthy male smokersEur J Clin Nutr.(2004 Dec)

Blood Flow - Fernandes PR, Lira FA, Borba VV, Costa MJ, Trombeta IC, Santos Mdo S, Santos Ada CVitamin C restores blood pressure and vasodilator response during mental stress in obese childrenArq Bras Cardiol.(2011 Jun)

Blood Flow - Mullan BA, Ennis CN, Fee HJ, Young IS, McCance DRPretreatment with intravenous ascorbic acid preserves endothelial function during acute hyperglycaemia (R1)Clin Exp Pharmacol Physiol.(2005 May-Jun)

Blood Flow - Stamatelopoulos KS, Lekakis JP, Papamichael CM, Papaioannou TG, Cimboneriou A, Stamatelopoulos SFOral administration of ascorbic acid attenuates endothelial dysfunction after short-term cigarette smokingInt J Vitam Nutr Res.(2003 Nov)

Blood glucose - Pleiner J, Schaller G, Mittermayer F, Bayerle-Eder M, Roden M, Wolzt MFFA-induced endothelial dysfunction can be corrected by vitamin CJ Clin Endocrinol Metab.(2002 Jun)

Pre-Eclampsia Risk - Kalpdev A, Saha SC, Dhawan VVitamin C and E supplementation does not reduce the risk of superimposed PE in pregnancyHypertens Pregnancy.(2011)

Anti-Oxidant Enzyme Profile - Ruiz-Ramos M, Vargas LA, Fortoul Van der Goes TI, Cervantes-Sandoval A, Mendoza-Nunez VMSupplementation of ascorbic acid and alpha-tocopherol is useful to preventing bone loss linked to oxidative stress in elderlyJ Nutr Health Aging.(2010 Jun)

Bone Mineral Density - Chuin A, Labonté M, Tessier D, Khalil A, Bobeuf F, Doyon CY, Rieth N, Dionne IJEffect of antioxidants combined to resistance training on BMD in elderly women: a pilot studyOsteoporos Int.(2009 Jul)

Body Fat - Knab AM, Shanely RA, Jin F, Austin MD, Sha W, Nieman DCQuercetin with vitamin C and niacin does not affect body mass or compositionAppl Physiol Nutr Metab.(2011 Jun)

Bacterial Vaginosis Symptoms - Petersen EE, Genet M, Caserini M, Palmieri REfficacy of vitamin C vaginal tablets in the treatment of bacterial vaginosis: a randomised, double blind, placebo controlled clinical trialArzneimittelforschung.(2011)

General Oxidation - Monika Lagowska-Lenard, Zbigniew Stelmasiak, Halina Bartosik-PsujekInfluence of vitamin C on markers of oxidative stress in the earliest period of ischemic strokePharmacol Rep.(Jul-Aug 2010)

Upper Respiratory Tract Infection Risk - Coulehan JL, Reisinger KS, Rogers KD, Bradley DWVitamin C prophylaxis in a boarding schoolN Engl J Med.(1974 Jan 3)

Depression Symptoms - Brody SHigh-dose ascorbic acid increases intercourse frequency and improves mood: a randomized controlled clinical trialBiol Psychiatry.(2002 Aug 15)

Cataract Risk - Christen WG, Glynn RJ, Sesso HD, Kurth T, MacFadyen J, Bubes V, Buring JE, Manson JE, Gaziano JMAge-related cataract in a randomized trial of vitamins E and C in menArch Ophthalmol.(2010 Nov)

Triglycerides - Kim MK, Sasaki S, Sasazuki S, Okubo S, Hayashi M, Tsugane SLong-term vitamin C supplementation has no markedly favourable effect on serum lipids in middle-aged Japanese subjectsBr J Nutr.(2004 Jan)

Charcot Marie Tooth Disease Symptoms - Pareyson D, Reilly MM, Schenone A, Fabrizi GM, Cavallaro T, Santoro L, Vita G, Quattrone A, Padua L, Gemignani F, Visioli F, Laurà M, Radice D, Calabrese D, Hughes RA, Solari A; CMT-TRIAAL; CMT-TRAUK groupsAscorbic acid in Charcot-Marie-Tooth disease type 1A (CMT-TRIAAL and CMT-TRAUK): a double-blind randomised trialLancet Neurol.(2011 Apr)

Uric Acid - Han-Yao Huang, Lawrence J Appel, Michael J Choi, Allan C Gelber, Jeanne Charleston, Edward P Norkus, Edgar R Miller 3rdThe effects of vitamin C supplementation on serum concentrations of uric acid: results of a randomized controlled trialArthritis Rheum.(2005 Jun)

Uric Acid - Xin-Xin Liu, Xiao-Xue Wang, Ling-Ling CuiAssociation between Oral vitamin C supplementation and serum uric acid: A meta-analysis of randomized controlled trialsComplement Ther Med.(2021 Aug)

COVID-19 Severity - Saeidreza JamaliMoghadamSiahkali, Besharat Zarezade, Sogol Koolaji, SeyedAhmad SeyedAlinaghi, Abolfazl Zendehdel, Mohammad Tabarestani, Ehsan Sekhavati Moghadam, Ladan Abbasian, Seyed Ali Dehghan Manshadi, Mohamadreza Salehi, Malihe Hasannezhad, Sara Ghaderkhani, Mohsen Meidani, Faeze Salahshour, Fatemeh Jafari, Navid Manafi, Fereshteh GhiasvandSafety and effectiveness of high-dose vitamin C in patients with COVID-19: a randomized open-label clinical trialEur J Med Res.(2021 Feb 11)

COVID-19 Severity - Suma Thomas, Divyang Patel, Barbara Bittel, Kathy Wolski, Qiuqing Wang, Anirudh Kumar, Zachary J Il'Giovine, Reena Mehra, Carla McWilliams, Steve E Nissen, Milind Y DesaiEffect of High-Dose Zinc and Ascorbic Acid Supplementation vs Usual Care on Symptom Length and Reduction Among Ambulatory Patients With SARS-CoV-2 Infection: The COVID A to Z Randomized Clinical TrialJAMA Netw Open.(2021 Feb 1)

Weight - Huck CJ, Johnston CS, Beezhold BL, Swan PDVitamin C status and perception of effort during exercise in obese adults adhering to a calorie-reduced dietNutrition.(2012 Jun 5)

Subjective Well-Being - Zhang M, Robitaille L, Eintracht S, Hoffer LJVitamin C provision improves mood in acutely hospitalized patientsNutrition.(2011 May)

Sperm Quality - Vani K, Kurakula M, Syed R, Alharbi KClinical relevance of vitamin C among lead-exposed infertile menGenet Test Mol Biomarkers.(2012 Sep)

Microcirculation - Stewart JM, Ocon AJ, Medow MSAscorbate improves circulation in postural tachycardia syndromeAm J Physiol Heart Circ Physiol.(2011 Sep)

Spontaneous Birth Risk - Hauth JC, Clifton RG, Roberts JM, Spong CY, Myatt L, Leveno KJ, Pearson GD, Varner MW, Thorp JM Jr, Mercer BM, Peaceman AM, Ramin SM, Sciscione A, Harper M, Tolosa JE, Saade G, Sorokin Y, Anderson GB; Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) Maternal-Fetal Medicine Units Network (MFMU)Vitamin C and E supplementation to prevent spontaneous preterm birth: a randomized controlled trialObstet Gynecol.(2010 Sep)

Heart Rate - Gomes ME, El Messaoudi S, Lenders JW, Bellersen L, Verheugt FW, Smits P, Tack CJHigh dose ascorbic acid does not reverse central sympathetic overactivity in chronic heart failureJ Clin Pharm Ther.(2011 Oct)

Gout Symptoms - Stephen P Juraschek, J Michael Gaziano, Robert J Glynn, Natalya Gomelskaya, Vadim Y Bubes, Julie E Buring, Robert H Shmerling, Howard D SessoEffects of vitamin C supplementation on gout risk: results from the physicians' health study II trialAm J Clin Nutr.(2022 May 16)

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Bronchitis Symptoms - Wei J, Pang CS, Han J, Yan HEffect of Orally Administered N-Acetylcysteine on Chronic Bronchitis: A Meta-analysis.Adv Ther.(2019-Dec)

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Urinary NOx - Dimitrios Tsikas, Jonas Niemann, Markus Flentje, Alexandra Schwarz, Paschalis TossiosN-Acetylcysteine (NAC) inhibits renal nitrite and nitrate reabsorption in healthy subjects and in patients undergoing cardiac surgery: risk of nitric oxide (NO) bioavailability loss by NAC?Int J Cardiol.(2014 Nov 15)

Tobacco Addiction Symptoms - Knackstedt LA, LaRowe S, Mardikian P, Malcolm R, Upadhyaya H, Hedden S, Markou A, Kalivas PWThe role of cystine-glutamate exchange in nicotine dependence in rats and humansBiol Psychiatry.(2009 May 15)

Marijuana Addiction - Gray KM, Watson NL, Carpenter MJ, Larowe SDN-acetylcysteine (NAC) in young marijuana users: an open-label pilot studyAm J Addict.(2010 Mar-Apr)

Acne Symptoms - Ahmed Salih Sahib, Haidar Hamid Al-Anbari, Mohammed Salih, and Fatima AbdullahEffects of Oral Antioxidants on Lesion Counts Associated with Oxidative Stress and Inflammation in Patients with Papulopustular AcneJournal of Clinical and Experimental Dermatology Research .()

Depression Symptoms - Fernandes BS, Dean OM, Dodd S, Malhi GS, Berk MN-Acetylcysteine in depressive symptoms and functionality: a systematic review and meta-analysis.J Clin Psychiatry.(2016-Apr)

Cocaine Addiction Symptoms - Duailibi MS, Cordeiro Q, Brietzke E, Ribeiro M, LaRowe S, Berk M, Trevizol APN-acetylcysteine in the treatment of craving in substance use disorders: Systematic review and meta-analysis.Am J Addict.(2017-Oct)

Forced Expiratory Volume - Ciofu O, Smith S, Lykkesfeldt JAntioxidant supplementation for lung disease in cystic fibrosis.Cochrane Database Syst Rev.(2019-Oct-03)

Schizophrenia symptoms - Yolland CO, Hanratty D, Neill E, Rossell SL, Berk M, Dean OM, Castle DJ, Tan EJ, Phillipou A, Harris AW, Barreiros AR, Hansen A, Siskind DMeta-analysis of randomised controlled trials with -acetylcysteine in the treatment of schizophrenia.Aust N Z J Psychiatry.(2020-May)

Kidney Function - Magner K, Ilin JV, Clark EG, Kong JWY, Davis A, Hiremath SMeta-analytic Techniques to Assess the Association Between N-acetylcysteine and Acute Kidney Injury After Contrast Administration: A Systematic Review and Meta-analysis.JAMA Netw Open.(2022-Jul-01)

Helicobacter Pylori Infection Signs - Biswas DP, Tk DSThe efficacy of adjuvant N acetyl cysteine for the eradication of H pylori infections: A systematic review and meta-analysis of randomized clinical trials.Clin Res Hepatol Gastroenterol.(2022-Mar)

Liver Enzymes - Jia D, Guo S, Jia Z, Gao Z, You K, Gong J, Li SN-acetylcysteine in the Donor, Recipient, or Both Donor and Recipient in Liver Transplantation: A Systematic Review With Meta-analysis and Trial Sequential Analysis.Transplantation.(2023-May-08)

Length of hospitalization - Pereira JEG, El Dib R, Braz LG, Escudero J, Hayes J, Johnston BCN-acetylcysteine use among patients undergoing cardiac surgery: A systematic review and meta-analysis of randomized trials.PLoS One.(2019)

Cycling Performance - Rhodes K, Braakhuis APerformance and Side Effects of Supplementation with N-Acetylcysteine: A Systematic Review and Meta-Analysis.Sports Med.(2017-Aug)

Depression Symptoms - Nery FG, Li W, DelBello MP, Welge JAN-acetylcysteine as an adjunctive treatment for bipolar depression: A systematic review and meta-analysis of randomized controlled trials.Bipolar Disord.(2021-11)

Rate Of Pregnancy - Devi N, Boya C, Chhabra M, Bansal D-acetyl-cysteine as adjuvant therapy in female infertility: a systematic review and meta-analysis.J Basic Clin Physiol Pharmacol.(2020-Nov-19)

Testosterone - Zahra Shahveghar Asl, Karim Parastouei, Eslam EskandariThe effects of N-acetylcysteine on ovulation and sex hormones profile in women with polycystic ovary syndrome: a systematic review and meta-analysisBr J Nutr.(2023 Jan 4)

Neuropathic Pain Symptoms - Mohiuddin M, Pivetta B, Gilron I, Khan JSEfficacy and Safety of N-Acetylcysteine for the Management of Chronic Pain in Adults: A Systematic Review and Meta-Analysis.Pain Med.(2021-Dec-11)

Forced Vital Capacity - Rogliani P, Calzetta L, Cavalli F, Matera MG, Cazzola MPirfenidone, nintedanib and N-acetylcysteine for the treatment of idiopathic pulmonary fibrosis: A systematic review and meta-analysis.Pulm Pharmacol Ther.(2016-Oct)

Hearing Loss - Kranzer K, Elamin WF, Cox H, Seddon JA, Ford N, Drobniewski FA systematic review and meta-analysis of the efficacy and safety of N-acetylcysteine in preventing aminoglycoside-induced ototoxicity: implications for the treatment of multidrug-resistant TB.Thorax.(2015-Nov)

Hearing Loss - Chang PH, Liu CW, Hung SH, Kang YNEffect of N-acetyl-cysteine in prevention of noise-induced hearing loss: a systematic review and meta-analysis of randomized controlled trials.Arch Med Sci.(2022)

Hearing Loss - Bai X, Wang M, Niu X, Yu H, Yue JX, Sun YEffect of N-acetyl-cysteine treatment on sensorineural hearing loss: a meta-analysis.World J Otorhinolaryngol Head Neck Surg.(2022-Sep)

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